Postdoctoral Research Assistant in Cell and Developmental Biology
University of Dundee -Life Sciences Research
Grade 7 (£29,541 - £36,298)
We are seeking an outstanding and highly motivated postdoctoral researcher for an MRC-funded project to study the regulation of Rho family small GTPases by Fibroblast-growth factor (FGF) signaling in epithelial-mesenchymal transition (EMT). Research in our laboratory has shown that the Drosophila Rho-guanine-nucleotide exchange factor Pebble, the highly conserved fly homolog of the proto oncogen ECT2, plays a key role in FGF-dependent EMT during early mesoderm development (Curr. Biol. 14, 659; Development 131, 2631; Development 136, 813; Phys Biol 8, 045001). The project offers the opportunity to apply genetics, high-resolution live imaging and quantitative proteomics to discover the molecular mechanism that control Pebble activity and determine its cellular functions during EMT and collective cell migration.
The successful candidate will have a PhD or recently submitted a thesis to obtain a PhD degree. We expect the ideal candidate to have excellent communication skills, to work in a team, but also to plan and perform experiments independently. A preference will be for candidates with previous experience either in state-of-the-art Drosophila genetics, proteomics, or in high resolution/live imaging techniques.
The position is open from September 2013 and will available for 2 years.
For informal requests please contact Dr. Arno Muller at h.j.muller@dundee.ac.uk.
