Postdoctoral Research Associate

Department of Biochemistry, South Parks Road, Oxford

Grade 7: £29,541 - £36,298 p.a.

We are seeking to appoint a Postdoctoral Research Associate to join the Genome Stability Research Group led by Professor Matthew Whitby. In particular, we are looking for someone interested in working on the molecular mechanisms that drive homologous recombination at stalled replication forks and DNA double-strand breaks. The successful candidate will work on the reconstitution of recombination reactions in vitro using purified proteins, with a particular emphasis on elucidating the mechanisms that govern the processing of recombination intermediates. There will also be opportunities to complement this work with in vivo analysis using both genetic and cell biological techniques.

Applicants should possess: a PhD/DPhil in Biology, Biochemistry or related subject; postgraduate/postdoctoral experience in a relevant field and a high level of technical competence in standard molecular biology techniques, protein purification and protein biochemistry of DNA replication/recombination/repair proteins. The applicant should be highly motivated, willing to learn new techniques, have relevant experience demonstrated through appropriate peer-reviewed publications and be able to work both independently and as part of a team.

Experience working with fission yeast and expertise in fluorescence microscopy (including live cell imaging) are desirable.

This full-time post is funded by the Wellcome Trust for up to 12 months in the first instance and is based at the new biochemistry building, South Parks Road, Oxford.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

For further general information, phone 01865 613204, quoting reference number BR/555.

The closing date for applications is 12.00 midday on Monday 3 June 2013, with interviews for shortlisted candidates as soon as possible thereafter.