Postdoctoral Research Assistants

University of Dundee - MRC Protein Phosphorylation and Ubiquitylation Unit

Development and application of novel probes for profiling E3 ligases.

Applications are invited for multiple openings for Postdoctoral Research Assistants in the lab of Dr Satpal Virdee. Research will involve chemical proteomic platforms based upon powerful probe technology recently developed in his lab for profiling the activity of E3 ligases (Nature Chemical Biology 2016, 12, 324–331). Projects range from further probe development and application to a broader spectrum of enzymes, to biological investigation and characterization of E3 ligases implicated in disease relevant signalling pathways. Other projects involve extension of the probe technology to RING E3 ligases allowing the assignment of RING E3 ligases to their cognate substrates. The candidates should ideally have recently carried out a PhD working in the area of chemical biology, cell biology or biochemistry. Experience with mass spectrometry would also be beneficial. Chemical biology experience encompassing both organic synthesis and tissue culture techniques would be highly desirable. Regarding cell biology and biochemistry related projects, experience pertaining to the ubiquitin system would be preferential but not essential.

The successful applicants will join an international team in an exciting and interactive environment, equipped to the highest international standards.

For informal enquiries please contact Dr Virdee directly

Candidate requirements:

- PhD, with outstanding academic track record and at least one first authored publication in an internationally recognised journal.
- Capable of working in a team, but able to plan and work independently.
- Excellent communication skills and knowledge of the English language.

MRC Protein Phosphorylation and Ubiquitylation Unit (PPU):

This project will be performed in the MRC Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU), based within the School of Life Sciences at the University of Dundee. The MRC-PPU is in a beautiful location overlooking the estuary of the River Tay and embedded within the School of Life Sciences at the University of Dundee which is one of the premier Life Sciences research centres in the world.

These positions are available immediately and are for a fixed-term period of 3 years.

The appointment will be made on the Grade 7 salary scale with initial placement depending on achievements and experience, but will range from £31,076 – £38,183.

Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD. An appointment may be considered if you are shortly expected to be awarded a PhD. The initial appointment will be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 28, £30,175).

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