Scientific Officer 2: Development of Novel Biomarker Assays

The University of Manchester - Clinical and Experimental Pharmacology Group

  • Duration of post: Fixed term for 2 years (in the first instance)

The Cancer Research UK Manchester Institute (, an Institute of The University of Manchester (, is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (, the largest independent cancer research organisation in the world. We are adjacent to The Christie NHS Foundation Trust (, one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

Our aim is to understand the fundamental basis of cancer and apply that knowledge to developing new treatment strategies for cancer patients. Our advanced research programmes span a spectrum of cancer research, from the molecular and cellular basis of cancer through to drug discovery, translational research and clinical trials.

The Institute has outstanding laboratory facilities and exceptional core services, including next generation sequencing, microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry.

We are situated in Manchester, England, a vibrant and dynamic city that is surrounded by beautiful countryside and has excellent transport links both nationally and internationally.

The Clinical and Experimental Pharmacology Group (CEP) aim to enhance clinical trials of new anticancer drugs through biomarker research. A position is available for an experienced Scientific Officer to join our Cell & Protein Biomarkers Team, and oversee our effort on the development of novel biomarker assays, complementing in-house technology for ‘rare cell’ enrichment from cancer clinical trial samples, with a view to deploying the assays on samples from a new clinical trial. All the required training and supervision will be provided.

The successful candidate will possess a bachelor’s degree in an appropriate scientific discipline or equivalent relevant experience, e.g. biology, biochemistry, or medical sciences. Also required is first-hand experience of a range of immune assays in the laboratory, including immunocytochemical and immunofluorescent, along with a track record of success in the implementation and utilisation of such assays, e.g. in a clinical setting or for research publications. Highly desirable is previous experience of working in a cancer research setting, ideally to Good Clinical Practice (GCP) standards. Also desirable is experience of qualitative and quantitative image analysis, and familiarity with computer databases in a laboratory setting, e.g. Laboratory Information Management Systems (LIMS).

Informal enquiries should be directed to Dr Jonathan Tugwood, email:

To apply for this position please visit our website:

For applicants who are unable to download this information from our website, please contact HR department on 0161 446 3231 or, email: to have this information sent by post.

Deadline for receipt of applications is: 11 November 2016.

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