PhD Studentship in cell mechanics

University of Cambridge - Department of Engineering

Cellular adhesion is central in many biological scenarios, including tissue integrity, cell migration or blood flow regulation. These processes are important components of the mechanics that govern cancer expansion and invasion, the occurrence of some cardiovascular diseases, and the course of embryonic development.

There are two goals in this project. First, the student will implement a new instrument to quantitatively assess adhesion at a single cell level. The new instrument will be micro-fabricated, calibrated and used to perform highly precise measurements on a variety of cell types, and under specific conditions that closely mimic biological situations. The second goal is to subsequently devise a theoretical model for the adhesive forces that can capture general principles of cellular adhesion.

The project is both experimental and theoretical, intrinsically multidisciplinary, and we anticipate frequent interactions with biologists during the studentship.

For further information, contact Dr Thierry Savin t.savin@eng.cam.ac.uk

Applicants should have, or expect to obtain by the start date, a first class or a high 2:1, honours degree (preferably at Master's degree level) in an Engineering or Physics subject.

This EPSRC funded studentship is available for Home and EU students. Home students and  certain EU students will receive a full studentship including fees and Maintenance. EU students will receive a fees only award. Details on eligibility can be found of EPSRC Web site: https://www.epsrc.ac.uk/skills/students/help/eligibility/ Overseas Students are not eligible and should not apply

Applications should be made on-line via the Cambridge Graduate Admissions Office before the deadline: http://www.admin.cam.ac.uk/students/gradadmissions/prospec/apply/ with Thierry Savin identified and the potential supervisor

The University values diversity and is committed to equality of opportunity.

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Type / Role:

PhD

Location(s):

South East England