Drug Discovery Project Leader – Molecular and Cell Biology

The Beatson Institute for Cancer Research

The Drug Discovery Unit at the Beatson Institute in Glasgow, is a Cancer Research UK funded group of ex-industry and specialist academic scientists in Biology, Chemistry and Structural Biology. 

The aim of this unit is to work closely with local cancer experts to maximise the opportunity to develop new and innovative therapies that strike at the core of cancer pathology. Using state of the art screening and structural biology technology, industry standard medicinal chemistry and complex biological modelling systems, the Drug Discovery group at the Beatson is tackling some of the most challenging targets in cancer biology today. An opportunity has arisen to appoint a molecular and cell biologist at a senior level within the group.

If you are a highly skilled, enthusiastic scientist who takes an innovative and proactive approach to research challenges, then we would like to hear from you.

We are looking for a highly experienced molecular and cell biologist with a track record of leading drug discovery or translational projects.

Ideally you will have worked in industry and demonstrated effective leadership within a biology team. In parallel, you should be a highly experienced bench scientist with the ability to apply current molecular biology and functional cell assay techniques to address target validation and compound screening objectives.

The role will involve working as part of a multidisciplinary team with chemists and structural biologists to develop functional cell assays within defined project parameters. You will need to keep thoroughly up to date with the relevant biological and technological literature and take a creative problem solving approach to develop assays for novel and challenging targets.

You will also be involved in validation of potential new drug targets, working closely with Institute Principal Investigators to demonstrate the importance of these drug targets in key cellular processes of cancer.

Consistent and robust experimental technique, attention to detail and an innovative and forward thinking approach to experimental challenges are essential for this role.

Skills and Experience :

  • Ph.D. in a relevant biological discipline.
  • Additional experience within the pharmaceutical industry or an equivalent translational research environment.
  • Experienced in a wide range of mammalian cell culture systems including proliferation, migration, invasion and viability and involving a diverse range of cell types, ideally cancer cell lines.
  • Highly competent in mammalian cell transfection and plasmid design, and experienced in the use of RNAi.
  • Knowledge of cancer biology, cell pathology and signalling pathways.
  • Excellent communication and leadership skills, including experience of working as part of multidisciplinary team are highly valued.

Applications must be made via our website http://www.beatson.gla.ac.uk/Careers/Drug-Discovery/

Informal enquiries are welcome and should be addressed to Dr Heather McKinnon; h.mckinnon@beatson.gla.ac.uk (Head of Biology).

Closing date for applications is Friday December 16th, 2016.

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