Research Associate - Drug Induced Mitochondrial Toxicity in the Context of Hypoxia (Fixed Term)

University of Cambridge - Department of Physiology, Development and Neuroscience

We are looking for a post-doctoral Research Associate to join a highly-innovative, collaborative project based in Cambridge at the Department of PDN but also working in association with the Departments of Biochemistry and Medicine, and with industry partners, GSK and AstraZeneca. The academic Principal Investigator for the project is Dr Andrew Murray, whose group work on mitochondrial function with a particular interest in understanding how mitochondria are altered under hypoxic conditions (www.pdn.cam.ac.uk/directory/andrew-murray). The academic co-Investigators are Prof Margaret Ashcroft (Medicine), an expert in hypoxia signalling and Prof Julian Griffin (Biochemistry) whose group specialise in metabolomics with a strong interest in metabolic diseases. The Industrial lead investigators are Dr Jon Lyon (GSK), Dr Lindsay Edwards (GSK) and Dr Dominic Williams (AstraZeneca).

The successful applicant will have a PhD in biochemistry, physiology, molecular cellular biology or related field. A background in mitochondrial biology and experience of performing in vivo experiments with rodents and handling large datasets are essential. Experience with either isolated organs, tissue and cell culture or mass spectrometry is desirable; however appropriate training will be provided for the successful candidate.

Prior experience of working within multi-collaborative teams or working within the pharmaceutical industry (eg as an industrial placement student) would be beneficial.

The post is funded by GSK and is available for two years in the first instance with possibility of funding for a further year.

Fixed-term: The funds for this post are available for 2 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.

To apply online for this vacancy and to view further information about the role, please visit:

www.jobs.cam.ac.uk/job/12193. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

Please upload your CV, publication list and research statement in the upload section.

Please quote reference PM10794 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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South East England