Informatics Engineer

University of Edinburgh - Centre for Clinical Brain Sciences

Full time, fixed term for three years

The role: We seek a talented and experienced Informatics Engineer to join our team at this exciting stage of our research into the fundamental principles linking the molecular organization of synapses with brain architecture.The successful candidate will work closely with our Research Scientists and Image Analysis Developer to build a dedicated web database to disseminate mapping data resources, manage network and data storage systems, and support the optimization of data analysis platform for synapse mapping.

The study of synapses has been central to understanding the biology of the brain. Recent research has revealed that synapses are built from ~1000 proteins causally linked to over 130 brain diseases including childhood developmental disorders. We developed a transformative technology pipeline for visualizing proteins expressed in individual synapses in brain tissue sections and mapping these at the whole brain scale, in health and disease, in mice and humans. The prototype pipeline called “G2CSynMAPP”, utilizes advanced biochemical, optical and computational technologies. Using the G2CSynMAPP we have, for the first time, generated comprehensive maps (~50 Terabytes) of individual synapses across the whole mouse brain at different levels of complexity. Our tools and resources are now in high demand from the scientific and medical communities both locally, nationally and internationally.

The candidate profile: This position requires a university degree or equivalent experience in computer science, informatics or another related discipline. The candidate we require should have proven experience in website and database development and management. A background in supporting optimization of image software to improve algorithmic efficiency of big data analytics and experience of working with biomedical images and participation in joint projects would be advantageous. 

The post holder will be joining a team which includes experts in mouse molecular genetics, biochemistry, synapse biology and quantitative image analysis. The successful candidate should have experience in working within a research group and be driven by a collegiate, collaborative ethos, and be an independent individual committed to research. The chosen candidate will be based in the Centre for Clinical Brain Sciences at University of Edinburgh (

Enquiries are welcome and can be sent to Seth Grant at  

Closing Date: Wednesday 4th January 2017

For more information and to submit an application, please use the ‘apply’ button below.

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