Postdoctoral Computational Cancer Biologist

University of Oxford - Radcliffe Department of Medicine

MRC Weatherall Institute of Molecular Medicine
MRC Molecular Haematology Unit
John Radcliffe Hospital
Headington

Applications are invited for a Computational Cancer Biologist in a programme funded by the Wellcome Trust. We are seeking a team player to analyse RNA-seq data from human cancers within the group of Professor Terry Rabbitts based at the MRC Weatherall Institute of Molecular Medicine (WIMM). The objective is to find mRNA encoding proteins on the cancer cell surface that serve as markers for antibody-mediated therapy and for uptake of nanoparticles into cells for cargo delivery. Single cell RNA-seq and DNA-seq will be part of the project.

Candidates must have a PhD degree in a relevant biological or computational subject and practical experience of bioinformatics analysis of Next Generation Sequence data. Experience with computational, statistical and mathematical methods together with RNA-seq, NGS data analysis and R is essential. Additionally, experience in using LINUX or UNIX is also essential. An understanding of cancer cell and molecular biology and a working knowledge of protein structure/function is desirable to inform selection of candidates for cell-based studies within the group. The post will be ideally suited to an adaptable scientist who wishes to be able to link the surfaceome sequence data mining with the molecular biology widely used with in the research group. The post could be suitable for a wet-lab scientist who has experience of RNA-seq analysis but wishes to move into bioinformatics (further training is available in collaboration with the WIMM Computational Biology Research Group).

The post is available on fixed-term basis for 2 years. Preliminary enquiries should be made to: terence.rabbitts@imm.ox.ac.uk.

Applications for this vacancy are to be made online. You will be required to upload a CV and a supporting statement as part of your online application.

The closing date for this position is 12.00 midday on 9 December 2016. Interviews will be held during week commencing 2 January 2017.

www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=126386

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