Senior Bioscientist - Assay Development and Compound Profiling (Drug Discovery Unit)

The University of Manchester

  • Duration: fixed term until March 2019

We’re currently looking for a Senior Bioscientist to join the Drug Discovery Unit to provide enzymology and biophysical support to our oncology focussed drug discovery programs. The post holder will be responsible for the development of novel biochemical assays, performing medium throughput screens and target-ligand mechanism of action studies. Significant experience in these areas coupled with a strong knowledge of enzyme kinetics applied to mechanism-of-action studies, and a background in elucidating small molecule-protein binding interactions through biophysical approaches are desired.

This post would suit a highly motivated, conscientious and well organised individual, who is looking for the opportunity to support the day-to-day running of a busy drug discovery laboratory. Ideally, the post holder will have prior experience of working in an industrial drug discovery environment.

The successful candidate will possess a degree in a Biological discipline (or equivalent relevant experience) and will be proficient in assay development and have significant compound profiling experience.

For any informal enquiries about this post, please contact either recruiting line manager Dr Graeme Thomson, Team Leader (Biochemistry) via email at graeme.thomson@cruk.manchester.ac.uk or Dr Ian D Waddell, Drug Discovery Unit Head of Biology via email at ian.waddell@cruk.manchester.ac.uk.

The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are adjacent to The Christie NHS Foundation Trust (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. The Drug Discovery Unit employs state-of-the-art facilities directed toward the discovery of novel, clinically relevant treatments for a variety of different cancer types. Details of the Unit itself can be found at (http://www.cruk.manchester.ac.uk/Research/CRUK-MI-Groups/Drug-Discovery/Home).

The Institute has outstanding laboratory facilities and exceptional core services, including next generation sequencing, microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry. We are situated in Manchester, England, a vibrant and dynamic city that is surrounded by beautiful countryside and has excellent transport links both nationally and internationally.

To apply for this position please visit our website: www.cruk.manchester.ac.uk

For applicants who are unable to download this information from our website, please contact HR department on 0161 446 3231, email: jobs@cruk.manchester.ac.uk to have this information sent by post.

The deadline for receipt of applications is: 04 January 2017

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