PhD Studentship: Targeting the IRF4 Transcriptional Network to Subvert Multiple Myeloma

University of Sussex - Biochemistry/Molecular Biology

A Ph.D. studentship (42 months) is available from September 2017 under the supervision of Dr Erika Mancini, Department of Biochemistry, School of Life Sciences.

Deadline: 12th January 2017

An exciting PhD studentship, at the intersection between Myeloma Research, Structural Biology and Drug Discovery, is available in the School of Life Sciences at the University of Sussex. The PhD will be jointly supervised by Dr Erika Mancini, within the Department of Biochemistry and Dr Tim Chevassut, at the Brighton and Sussex Medical School. The aim of the project will be to establish a mechanistic understanding of the network of proteins whose transcription regulation is subverted in Multiple Myeloma, an aggressive and incurable cancer of plasma cells with rising national incidence. We will target key players and solve crystal structure of relevant transcription factor complexes to identify potential drug targets in Multiple Myeloma.

Please submit a formal application using our online application system at http://www.sussex.ac.uk/study/pg/applying/, including a CV, statement of interest and names of two academic referees. Please contact Alice Caryer (a.caryer@sussex.ac.uk) with any application queries.

On the application system use Programme of Study – PhD BIOCHEMISTRY.

Please make sure you include the project title and Supervisor’s name with your statement of interest on the application form.

This School funded position, which covers fees and a stipend at standard RCUK rates, is open to Home/EU applicants. Ideal candidates will have a strong background in molecular biology and biochemistry with additional experience of molecular haematology or crystallography being a distinct advantage. Eligible candidates will have recently received an MSc and/or a First or high 2:1 BSc in a relevant subject.

Please make sure you include the project title and supervisor’s name with your statement of interest on the application form.

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Advert information

Type / Role:

PhD

Location(s):

South East England