MRC Postdoctoral Fellow

University of Cambridge - MRC Mitochondrial Biology Unit

The University of Cambridge wishes to appoint a postdoctoral scientist to join Dr Julien Prudent's Mitochondrial Physiology research group in the MRC Mitochondrial Biology Unit in Cambridge. 

The post holder will work within a programme entitled "Mitochondrial dynamics and inter-organelle contacts in metabolism and death". Mitochondria are highly dynamics organelles constantly adapting their shape through fusion/fission events, to ensure their physiological functions. A critical discovery in the field of mitochondrial cell biology has been the identification of transient and specialized molecular structures connecting mitochondria with other organelles. Numerous of these inter-organelles contacts have been identified and functionally linked to mitochondrial functions, including apoptosis and cell survival. The goal of the project is to understand the regulations and functions of mitochondrial dynamics and inter-organelle contacts during cell survival and death events. Developing biochemical, cell biology and advanced microscopy methods, the post-holder will undertake research to study mitochondrial ultrastructure and organelle contact sites adaptations during different metabolic states. The associated-mechanisms regulating these morphological transitions will be investigated.

Candidates will have (or be about to be awarded) a PhD in biochemistry, cell biology or molecular biology, and a track record of related research achievements. Experience in classical biochemical, molecular and cell biology techniques is required. Knowledge in mitochondrial physiology, including dynamics and metabolism and strong experience in microscopy analysis is essential.

This is a fixed term training programme post for 3 years from date of appointment.

The MRC Mitochondrial Biology Unit is a world-renowned centre for research in respiratory enzymes. Additional information can be found at www.mrc-mbu.cam.ac.uk.

Fixed-term: The funds for this post are available for 3 years in the first instance.

To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/14445. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

The closing date for applications is 6th September 2017. The date of interview is TBC.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please quote reference SM12831 on your application and in any correspondence about this vacancy.

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