Research Assistant in Myeloid Neoplasias

University of Oxford - Radcliffe Department of Medicine

We are seeking a motivated and enthusiastic Research Assistant to work on a joint project between the laboratories of Professor Claus Nerlov and Professor Paresh Vyas on genetic modelling of myeloid malignancies.

The MRC Weatherall Institute of Molecular Medicine is a research institute undertaking research into the processes underlying normal cell and molecular biology and its aim is to determine the mechanisms by which these processes are perturbed in inherited and acquired human diseases. The Molecular Heamatology Unit is a world-leading centre of research into the causes and treatment of blood disorders, and myeloid malignancies in particular. The post holder will be responsible for generation and analysis of genetically accurate models of acute myeloid leukaemia and myeloproliferative disorders, using state-of-the-art genetic and functional genomics approaches, including CRISPR-Cas9–based genome engineering and single cell transcriptome analysis.

Candidates will hold a degree in a biomedical related area and have previous experience in the field of hematopoiesis, preferably including work on myeloid malignancies, and will be proficient in genetic, molecular biology and flow cytometry techniques. Experience with bioinformatics would be desirable. The ability to work as a team member and independently together with excellent organisation and communication skills are essential to the post. Most importantly, the post holder will have a high level of commitment to work and a true passion for furthering scientific research.

The post is available fixed-term for 12 months, funded by the Oxford Biomedical Research Centre (BRC) and departmental funds.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

The closing date for this position is 12.00 midday on Wednesday 30 August 2017.

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South East England