University of Cambridge - Department of Paediatrics

Applications are invited for the post of an Academic Related Bioinformatician to work on a collaborative translational research project between the groups of Dr Matthias Zilbauer (Department of Paediatrics at the University of Cambridge, UK), Dr Paul Lyons (Department of Medicine, University of Cambridge, UK) and Dr Oliver Stegle (European Bioinformatics Institute - EBI, UK). 

The overall aim of this project is to apply genome wide/whole genome profiling approaches to a large, prospectively recruited human tissue sample collection in order to investigate disease pathogenesis as well as develop clinical biomarkers for patients suffering from Inflammatory Bowel Diseases (IBD). A second focus lies on elucidating the role of epigenetic mechanisms in regulating cellular function in the human intestinal tract during physiological development and disease using human organoid culture models.

The selected candidate will have the opportunity to work with a group of international leaders in the field of translational research (e.g. Kraiczy et al. Mucosal Immunology 2016, Baud A et al, PLoS genetics 2017, McKinney EF et al Nature 2015) and apply cutting edge computational biology approaches to unique datasets derived from disease relevant human tissue/cell samples.

We welcome applicants with diverse backgrounds including biology, biomedicine, computational biology, bioinformatics or mathematics who wish to further develop and apply their bioinformatic skills. Experience in data analysis using Bioconductor packages in R (e.g. RNA and DNA sequencing, gene regulation and expression analysis, and/or modeling) or any other programming language is desired.

Applicants should have interpersonal and communication skills, allowing them to interact with team members and should be able to work as part of a team as well as independently. Experience in manuscript preparation and or grant writing is desirable. We are open to flexible working arrangements.

Both the University of Cambridge and European Bioinformatics Institute EBI provide unique opportunities for training and personal development.

Informal enquiries can be addressed to Dr Matthias Zilbauer (


Matthias Zilbauer

Oliver Stegle

Paul Lyons

Fixed-term: The funds for this post are available for 2 years in the first instance.

To apply online for this vacancy and to view further information about the role, please visit: This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

Please ensure that you upload a covering letter and CV with a brief statement outlining key areas of expertise and reasons why you would like to join the group in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Closing date for applications is the 21st August 2017, with interviews likely to be held between the 29th and 31st of August 2017.

Please quote reference RP13043 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Share this job
  Share by Email   Print this job   More sharing options
We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:


South East England