Postdoctoral Scientist in Stem Cell Biology - Investigating the Development of the Haematopoietic System

The University of Manchester - Cancer Research UK Manchester Institute

  • Commencement of post: January 2018
  • Duration of post: 3 years (in first instance) 

We are looking for a highly motivated Postdoctoral Scientist to join the laboratory of Professor Georges Lacaud to investigate the development of the haematopoietic system. Understanding how blood cells are generated is important from a biological perspective but has also tremendous potential implications for the treatment of blood diseases. The successful candidate will perform single cell expression and epigenetic analyses, in collaboration with our Bioinformatician, to reveal new hierarchical relationships, infer pathways of differentiation and uncover new regulatory interactions sustaining blood development. The hypotheses generated in silico will be evaluated using state-of-the-art mouse models, CRISPR genome editing and ES cell cultures. 

The applicant should have a PhD in molecular or cellular biology. A background in developmental haematopoiesis is desirable but not required. 

Informal enquiries should be directed to Georges Lacaud (georges.lacaud@cruk.manchester.ac.uk). 

The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are currently situated at the internationally-renowned life sciences campus at Alderley Park in Cheshire, England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside. We are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK Manchester Institute, Paterson Building) in South Manchester (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes. 

Our aim is to understand the fundamental basis of cancer and apply that knowledge to developing new treatment strategies for cancer patients.  Our advanced research programmes span a spectrum of cancer research, from the molecular and cellular basis of cancer through to drug discovery, translational research and clinical trials. 

The Institute has outstanding laboratory facilities and exceptional core services, including next generation sequencing, microarrays, confocal microscopy, bioinformatics, histology and mass-spectrometry. 

To apply for this position please visit our website: www.cruk.manchester.ac.uk 

For applicants who are unable to download this information from our website, please contact HR department on 0161 306 0840, email: jobs@cruk.manchester.ac.uk to have this information sent by post. 

Closing date: 25 September 2017.

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