Postdoctoral Research Associate in Protein Engineering to Control Immune Signalling

University of Oxford - Department of Biocehmistry

We are seeking to appoint a Postdoctoral Research Associate to create a new generation of protein assemblies to understand and control T cell activation. Through engineering and harnessing ultra-stable protein interactions, including Streptavidin/Biotin and SpyTag/SpyCatcher, the project will create giant programmable protein structures. These assemblies will then be used to give precise spatial control over stimulatory and inhibitory signals for T cell signalling, in collaboration with Professor Anton van der Merwe in the Sir William Dunn School of Pathology at the Oxford University. Such approaches should create powerful tools for detection and activation/inhibition of specific immune responses in health and disease.

Applicants should possess, or expect to obtain soon, a PhD in biochemistry, cell biology, immunology or a related area. They should be familiar with standard molecular biology approaches, recombinant protein expression, and protein chromatography and they should have applied these in their research. Skills and experience in cell culture and cell biological analysis are advantageous, but this is not required.

This full-time fixed-term post is funded by the BBSRC up until December 2018, with the intention to apply for future funding thereafter.

Further particulars, including details of how to apply, can be obtained from the document below.

The closing date for applications is 12.00 noon on Monday 25 September 2017, with interviews for shortlisted candidates to be held as soon as possible thereafter.

Please note that the University of Oxford's retirement policy is changing. With effect from October 1 2017, all employees at Grade 8 and above will have a retirement age of 68, and all employees at Grades 6 and 7 will no longer have a set retirement age. Further details are available at: www.ox.ac.uk/about/jobs/preemploymentscreening.

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=130799

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South East England