Postdoctoral Research Associate

King's College London - Richard Dimbleby Research Labs, Division of Cancer Studies

The salary will be paid at Grade 6, £33,518 to £39,992 per annum, plus £2,923 per annum London Allowance.

This post will be Fixed Term Contract for 2 years

This is a Full-time post

Biophysics, bioengineering, Life-science interface/ cancer

As part of an ambitious multidisciplinary programme of research to analyse and manipulate isolated exosomes (extracellular vesicles) and funded by Cancer Research UK, we are seeking an exceptional post-doctoral researcher to develop innovative cell imaging techniques using the latest technology. Interest in, or experience of advanced microscopy, microfluidics, biophysics, optics, optical trapping and computer programming is desirable. No prior biological experience is expected or required but an enthusiasm to apply physical and engineering principles to specific biological problems is essential. This project will explore the application of advanced imaging techniques such as high-speed multifocal multiphoton fluorescence lifetime imaging, programmable array microscopy, development and validation of FRET assays, super-resolution imaging and signal processing to elucidate protein signalling within exosomes. Such a multimodal and multidisciplinary approach will enable us to accurately determine protein receptor oligomerisation and stoichiometry of ligand-driven receptor interactions. Ultimately the project aims to apply these principles to real-world liquid biopsy monitoring of cancer patients in on-going clinical trials. The successful candidate will join a multidisciplinary team within a well-equipped laboratory environment using state of the art bespoke microscopy to answer fundamental questions of relevance to personalised cancer medicine.

The selection process will include a presentation and a panel interview.

Interviews are scheduled to be held the week commencing: 16 October 2017.

For an informal discussion to find out more about the role please contact Dr Simon Ameer-Beg (Simon.ameer-Beg@kcl.ac.uk)

To apply for this role, please go to the King’s College London HireWire Job Board and register to download and submit the specified application form.

The deadline for applications is midnight on 8 October 2017.

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