Postdoctoral Fellow on project "Discovery of Novel Plasma Protein Biomarkers of Venous Thromboembolism”

The University Hospital of North Norway – K.G.Jebsen-Thrombosis Research and Expertise Center (TREC)

Universitetssykehuset Nord-Norge HF (UNN) tilbyr befolkningen i den nordligste landsdelen medisinsk diagnostikk og behandling ved våre sykehus i Tromsø, Narvik, Harstad og Longyearbyen. Vår visjon er å gi den beste behandling, der resultatet for pasienten er det som teller. De rundt 6.500 medarbeiderne i UNN skaper resultater gjennom kontinuerlig forbedringsarbeid, internt samarbeid og tett samhandling med kommunehelsetjenesten og andre samarbeidspartnere. Les mer om oss.

K.G.Jebsen TREC - www.uit.no/research/trec - is a Research Center in translational medicine funded by the Kristian Gerhard Jebsen Foundation, UiT – the Arctic university of Norway, and the North Norwegian Health Authorities. K.G.Jebsen TREC has 3.2 permanent scientific positions (professors), 2 technical positions, and 15-20 temporary scientific positions (PhD-students and postdoctors). In addition, K.G.Jebsen TREC has partners in Tromsø, Bodø, Oslo, Leiden (The Netherlands), Chapel Hill (USA) and San Diego (USA). Professor John-Bjarne Hansen is the head of K.G.Jebsen TREC.

The University Hospital of North Norway has a Postdoctoral Research Fellow position vacant. The position is attached to the K.G.Jebsen TREC-Thrombosis Research and Expertise Center at the Department of Internal Medicne. The position of Postdoctoral Research Fellow is a fixed term position for a period of three years. The main objective of the appointment as a post-doctoral research fellow is to qualify for work in a senior academic position. No one will be appointed to more than one fixed term period as a Postdoctoral Research Fellow at the same institution. 

Venous thrombosis, a collective term for deep vein thrombosis and pulmonary embolism, is a prevalent disease With unclear pathogenesis and serious complications. The overall aim of K.G. Jebsen TREC is to identify novel inherited and environmental risk factors and extend the understanding of the pathogenesis in venous thrombosis. The research is organized in 4 work packages; 1. Genomics, 2. Microparticles and miRNA, 3. Inflammation and functional studies, and 4. Associations between arterial and venous thrombosis. The postdoctoral position will be connected to work package 3 – complement, inflammation and proteomics. 

The Application must be submitted electronically - use Apply for position - in this announcement - and shall include: 

  • letter of application 
  • CV (containing a complete overview of education, supervised professional training and professional work) 
  • diplomas and references 
  • list of works and description of these. The list of works shall contain the following information:
    • author(s), the work’s title
    • for articles: the journal’s name and volume, the first and last page of the article, year of publication
    • for publications: publisher, printer, year of publication, number of pages 
  • academic works: The applicant may submit up to ten works that are central to his/her production. The applicant’s doctoral thesis is regarded in this context as one work. 

In addition, the applicant shall provide a description of his/her production stating which works he/she considers the most important and which shall therefore be the main emphasis of the assessment. A brief description of the other listed works shall also be included to demonstrate depth of production.

Questions concerning the organisation of the working environment, such as the physical state of the place of employment, health service, possibility for flexible working hours, part time, etc. may be directed to the telephone reference in this announcement.

Job description

  • About the Project:
    Venous thrombosis (VTE), a collective term for deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common disease with serious complications such as the post-thrombotic syndrome, pulmonary hypertension, recurrence and death. In contrast to coronary artery disease (e.g. myocardial infarction), the incidence of VTE has not declined during the last decades. For many patients with life-threatening venous thrombosis, no risk factors can be identified. Thus, there is a major unmet need for discovery of novel plasma protein biomarkers to improve risk stratification and enable targeted prevention in order to reduce the incidence of VTE. The major objective of this project is to discover novel plasma protein biomarkers that could predict risk of first VTE at an individual level, and unravel novel mechanisms involved in the pathogenesis of VTE. The candidate is expected to have up to a one year research stay outside Norway with one of the partners of K.G.Jebsen TREC during the Project period.

Qualifications

  • For appointment as Postdoctoral Fellow, the applicant requires a Norwegian doctoral degree in a relevant area or a corresponding foreign doctoral degree recognised as equivalent to a Norwegian doctoral degree.
  • The Postdoctoral fellow will be involved in supervision of PhD students on similar projects and, in addition, is expected to develop a project proposal with a progress plan. It is required that the applicant will be able to complete the project during the period of appointment.
  • A PhD relevant for the project is required. Research experience with bioinformatics/proteomics is an advantage. The candidate is expected to possess good theoretical and practical capabilities within bioinformatics/proteomics or
  • molecular biology background with substantial experience with bioinformatics/proteomics.
  • The candidate must be able to work systematically, independently and have the ability to work in an interdisciplinary research team. Emphasis will also be placed on communicative and collaborative skills, as well as personal suitability. Experience with applications for external research funding will also be an advantage.
  • The candidate must speak and write English fluently.

We offer

  • Working conditions
    The working hours will be utilised for research, research-related activities and research administration. The successful applicant must be willing to engage himself/herself in the ongoing development of his/her discipline.
  • Assessment
    The applicants will be assessed by an expert committee. The committee’s mandate is to undertake an assessment of the applicants’ qualifications based on the written material presented by the applicants, and the detailed description drawn up for the position. The applicants who are assessed as the best qualified will be called to an interview. The interview shall among other things aim to clarify the applicant’s personal suitability for the position. A trial lecture may also be held.