Research Fellow in Cell Biology (76715-097)

University of Warwick - Warwick Medical School

Wellcome Trust Funded Research Fellow

You will join the laboratory of Professor Andrew McAinsh (Wellcome Trust Senior Investigator) in the Centre for Mechanochemical Cell Biology and Division of Biomedical Sciences at Warwick Medical School, making a positive contribution to their research, which aims to understand how kinetochores generate the forces necessary for chromosome segregation in human cells.

In particular, you will combine live-cell imaging using lattice light sheet microscopy, CRISPR/Cas9-medicated gene editing and in vitro microtubule-based assays to probe the mechanisms that drive chromosome movement in human cells. Your research will build on our recent discoveries concerning the function of the kinetochore Ska complex (Auckland et al, J. Cell Biol., 2017; Maciejowski et al, Dev. Cell, 2017) and the mechanical properties of the kinetochore-microtubule interface (Smith et al, eLife, 2016).

You will have good interpersonal skills and ability to work well in a research team enjoying critical but constructive conversation and the potential to produce publications in high-impact peer-reviewed journals.

You will have a PhD in a relevant field and a solid knowledge of cell biology and/or biophysics as evidenced from publications in frontline journals. Experience in live cell imaging, in vitro reconstitution, programming and/or development of image analysis tools would be a great asset.

Please include a full CV and a covering letter with your application form explaining how your skills meet the requirements, what you can bring to the post and why the post interests you.

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Midlands of England