Postdoctoral Research Associate in Computational Biochemistry

University of Oxford - Department of Biochemistry

South Parks Road

We are seeking to appoint a Postdoctoral Research Associate in computational biochemistry to investigate the dynamics and explore the atomic basis of kinetic control in ionotropic glutamate receptors. We are interested in applying computational methods to further our understanding of ionotropic glutamate receptors, and in particular the kainate subfamily. These receptors have been implicated in a variety of neurological disease states, but in particular epilepsy. A better understanding of what controls their conformational transitions should improve our prospects for the treatment of epilepsy significantly.

Applicants should possess or expect to obtain soon, a PhD in chemistry, biochemistry, physics or a related area, and should have extensive experience of molecular dynamics simulations and free energy calculations. You should also have the ability to drive a project forward, as well as work independently, and also contribute to a wider team ethic. As the project forms part of a larger ongoing collaboration, excellent communication skills and the ability to interact with people from different scientific backgrounds is an absolute requirement for the post. You should also have experience of python or a similar scripting language to automate large scale analysis. Experience of high performance computing, the MDAnalysis package and PLUMED would be highly desirable. Demonstrated competency with national computing resources and some system administration would also be advantageous.

This full-time fixed-term post is funded by the BBSRC for up to 8 months in the first instance.

Further particulars, including details of how to apply, can be obtained from the document below.

The closing date for applications is 12.00 noon on Monday 6 November 2017, with interviews for shortlisted candidates to be held as soon as possible thereafter.

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