Postdoctoral Research Fellow - DNA Repair Mechanisms

University of Sussex - School of Life Sciences

The School of Life Sciences is at the forefront of research in the biological sciences in the UK, coming in the top 10 in the REF 2014.

Postdoctoral Researcher: Deciphering the molecular mechanism of a novel DNA repair complex.

Applicants are invited to apply for a BBSRC-funded postdoctoral position to study DNA repair mechanisms. Cells possess a myriad of DNA repair pathways required to maintain genome stability.

The aim of this project is to study the molecular mechanism of a recently discovered DNA damage repair complex. Specifically, we would like to identify the components of this repair complex and define its molecular mechanism by reconstituting this repair process in vitro.

Applicants must have extensive experience in using biochemical, biophysical and molecular biology techniques to study the molecular interactions and mechanisms of protein complexes involved in DNA/RNA repair, replication, CrispR, transcription or related cellular processes.

The successful applicant will join the Genome Damage and Stability Centre, an internationally renowned Institute carrying out research on the response of cells to DNA damage, genome instability and its relationship to disease.

We provide a stimulating and supportive research environment and our expertise covers a wide range of experimental systems. Further information about our research can be obtained from our website at http://www.sussex.ac.uk/gdsc/.

Required qualifications for this position:

  • A PhD in biochemistry, structural biology or equivalent
  • A minimum of one first author publication in a reputable journal
  • Proven track record working on DNA/ RNA metabolising enzymes
  • Advanced skills in biochemistry and molecular biology
  • Highly motivated to work with protein complexes involved in DNA repair
  • Commitment to work in a highly competitive field.
  • Ability to independently drive a research project and analyse data
  • Fluent in written /spoken English and writing scientific reports/papers.

What we offer:

  • A highly motivated and dedicated international team.
  • Innovative projects at the forefront of this research field
  • Excellent collaborative research facilities and environment
  • Collaborations with many labs in our centre and abroad
  • A project where your contribution will make a real impact!

Informal enquiries to: Prof. Aidan Doherty

E-mail: AJD21@sussex.ac.uk;  Tel: +44 1273 877500.

The School is committed to equality and valuing diversity, and currently holds an Athena SWAN Silver Award. Applications are particularly welcomed from women and black and minority ethnic candidates, who are under-represented in academic posts in science and engineering at Sussex.  Part-time working will be considered.

The University offers various schemes to provide real benefits to parents, these can be found at http://www.sussex.ac.uk/humanresources/personnel/familyfriendlypolicies

For full details and how to apply see www.sussex.ac.uk/jobs

The University of Sussex is committed to equality of opportunity

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South East England