Research Associate

The University of Manchester - Diabetes, Endocrinology & Gastroenterology

Closing Date : 06/11/2017
Employment Type : Fixed Term
Duration : 1 January 2018 to 30 October 2020
Faculty / Organisational Unit : Biology, Medicine & Health
School/Directorate : School of Medical Sciences
Division : Diabetes, Endocrinology & Gastroenterology
Hours Per week : Full time
Salary : £31,604 to £32,548 per annum according to experience
Location : Oxford Road, Manchester
Job Reference : BM&H-10781

This is an opportunity for an enthusiastic and highly motivated individual to work on an MRC funded project in the laboratory of Professor Neil Hanley at the University of Manchester. The lab focuses on understanding human developmental mechanisms during post-implantation embryogenesis/ early foetal development. We have a major interest in providing detailed insight into human organogenesis to improve cell specific differentiation of human pluripotent stem cells (hPSCs) with the ultimate goal of cell replacement therapy. This project will build on recent published data (Jennings et al, Stem Cell Reports, 2017; Gerrard et al, Elife, 2016) to define the molecular framework of early human liver development. Using pioneered understanding and data from deep sequencing approaches directly on human embryo material alongside HLC differentiation from hPSCs it will build the first model of lineage differentiation directly in the early human liver for stem cell differentiation and liver cell programming platforms.

Your principle duties will be to design and carry out experiments for this research programme in a rigorous and efficient manner. You will have the desire to make new discoveries and present data in publications and oral presentations. You should have a BSc (hons) and PhD in a relevant biological sciences area and experience of managing a research project. Broad expertise in a wide range of cellular and molecular techniques is desirable including cell culture, cloning, PCR, protein detection, immunohistochemistry and gene regulation. Alongside this it would be an advantage to have experience of working with deep sequencing and transcriptomic analysis, single cell applications and stem cell culture / manipulation.

The School is committed to promoting equality and diversity, including the Athena SWAN charter for promoting women’s careers in STEMM subjects (science, technology, engineering, mathematics and medicine) in higher education. The School holds a Bronze Award for their commitment to the representation of women in the workplace and we particularly welcome applications from women for this post. Appointment will always be made on merit. For further information, please visit:

Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies

Enquiries about the vacancy, shortlisting and interviews:

Name: Professor Neil Hanley, Chair of Medicine


General enquiries:


Tel: 0161 275 4499

Technical support:


Tel: 01618502004

This vacancy will close for applications at midnight on the closing date

Further particulars including job description and person specification are available on the University of Manchester website - click on the 'Apply' button below to find out more.

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