Research Associate

University College London - Institute of Ophthalmology

The successful applicants will be involved in a project aimed at understanding the mechanisms through which leucine-rich alpha-2-glycoprotein 1 (LRG1) regulates pathological angiogenesis (see Wang et al., 2013. Nature 499:306-311). In particular, they will investigate how LRG1 corrupts the normal angiogenic process, its influence on vessel stabilization and maturation, crosstalk between endothelial cells and pericytes and the effect of therapeutic intervention on these processes. The project will involve the use of various in vivo ocular and cancer angiogenic models, cell and molecular biological techniques, cell signaling, and extensive microscopic techniques. The work will be carried out at UCL’s Institute of Ophthalmology.  The positions are funded by the Wellcome Trust for three years in the first instance.

Applicants must hold a PhD in a relevant subject area. Skills in vascular biology, angiogenesis or neovascularisation are essential. Experience in, cell signaling and confocal microscopy are desirable.

UCL vacancy reference: 1693824

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button below.

Informal enquiries about the post may be made to Professor John Greenwood (email: or Professor Stephen Moss (email: If you have any enquiries regarding the application process please email: .

Latest time for the submission of applications: 23:59.

Interview Date: 19 December 2017

Any offer of employment will be subject to a Disclosure and Barring Service (DBS) check.

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