Junior Consultant

Simcyp Limited

Line of Management: Consultant and Scientific Advisor

Holiday Entitlement: 25 days, plus statutory bank holidays

Job Overview:

We have an immediate opening for a Junior Consultant with good knowledge of drug metabolism and pharmacokinetics or biopharmaceutics. The candidate should have familiarity with in vitro-in vivo extrapolation (IVIVE) approaches and physiologically based pharmacokinetic (PBPK) modelling. Experience working in drug discovery/development within the Pharmaceutical Industry is desirable.

The successful candidate will join a multidisciplinary team which provides consultancy services centred on the application of PBPK modelling. The successful candidate will undertake a range of duties, including the collation, interpretation and analysis of data from a range of sources. The successful candidate will also be expected to become familiar with the Simcyp Simulator in order to develop skills and experience in the application of PBPK modelling. This role requires a high level of attention to detail, good oral and written communication skills and the ability to liaise effectively with external clients. The post does not include routine laboratory or clinical work.

We offer a unique and exciting mix of academic and commercial environments which encourage regular attendance at scientific meetings as part of our continuous education programs.



  • BSc (or equivalent experience) in a relevant field with significant practical experience.
  • Knowledge of in vitro assays used in drug metabolism and pharmacokinetic and/or biopharmaceutical studies and their application in IVIVE approaches.
  • Knowledge of PK/PD properties of small and/or large molecules
  • Demonstrable communication skills, as evident by presentation at scientific meetings, and good interpersonal and organizational skills.


  • Some understanding of modelling and simulation principles of physiological and biological systems and parameter estimation techniques.
  • Experience in prediction of drug-drug interactions.
  • Awareness of R&D process in pharmaceutical companies.

Company Overview:

Simcyp is part of Certara, a company which combines sophisticated research and development informatics with the power of predictive science methodologies to span the drug development spectrum and offer pharma a previously unavailable ‘end-to-end’ solution in the quest for improving human health. The Simcyp team conducts cutting-edge research and provides consultancy, knowledge integration tools, algorithms, modelling solutions and databases (implemented in its globally-recognised Simcyp Population-based Simulator) for a client base of major blue-chip pharmaceutical and biotechnology organisations. Simcyp focuses, in particular, on gathering information required for the modelling and simulation (M&S) of the individual time-course and fate of drugs. We are on course to become the global industry standard, consequently, there is a continuous requirement for high quality people to join us, help in our expansion and share in our success.

Applications: Please apply via our website OR send your CV, covering letter and the names of two references quoting the job reference/title and where you saw the position advertised to simcyp.recruitment@certara.com

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Northern England