PhD Studentship: Development of Smart Membranes for Controlled Drug Delivery

University of Bath - Department of Chemical Engineering

Supervisor: Bernardo Castro-Dominguez

The development of technologies with the capacity of controlling the release of drugs in a non-invasive, smart and programmable way is changing the field of drug delivery. Transdermal drug delivery devices are within these new technologies, since they have desirable traits such as avoidance of the gastrointestinal tract and improved patients’ compliance. A transdermal device consists of a patch/membrane capable of spreading a drug into the human body through the skin. Certainly, transdermal patches as non-invasive, but they still require a smart drug release control.

In this project you will develop transdermal patches with the capacity of releasing drugs in an on/off mode and in a controlled manner. By providing an external stimuli (heat, sound, electricity, light, pressure), the chemical and/or physical traits of the drug / membrane system can modified to tune the release of drugs. After identifying the stimuli needed, an integrated patch-stimulant device will be engineered, allowing its digital control. Although, no clinical tests are expected; the project is highly experimental and requires some modelling skills.

The development of this membranes requires a student with a strong background in chemistry, chemical engineering and material science. The ability to think outside the box is essential. Interested applicants, please contact Dr. Bernardo Castro directly before applying at B.Castro.Dominguez@bath.ac.uk.

A Home/EU award will provide full tuition fees, an annual Training Support Fee of £1,000, and a tax-free maintenance payment of £14,553 (2017-8 rate) for up to 3.5 years.

An Overseas award (3 years): Provides tuition fee, an annual Training Support Fee of £1,000, but no stipend.

The successful applicant will ideally have graduated (or be due to graduate) with an undergraduate Masters first class degree and/or MSc distinction (or overseas equivalent).

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Type / Role:

PhD

Location(s):

South West England