Post-Doctoral Research Associate

Aston University - Aston Medical School

Contract Type: Fixed Term (12 months)

Closing Date: 23.59 hours GMT on Tuesday 05 December 2017

Interview Date: To be confirmed

Aston Medical School (AMS) is located in the center of Birmingham and houses the University-wide Aston Medical Research Institute (AMRI). The schools overarching vision is to be internationally recognised for excellence and distinctiveness research to deliver scientific discoveries in Translational Medicine. The core themes of the AMRI are focused on Women's Health, Cardiovascular Health, Mental Health and Regenerative Medicine. The institute provides an excellent training and multi-disciplinary environment for translational research that transforms lives, addresses local health challenges with global impact.

Aston Medical School is seeking to appoint a Postdoctoral Research Associate for a new Regenerative Medicine Centre, a key research theme within Aston Medical Research Institute (AMRI). The central aim of this postdoctoral project is to investigate the molecular mechanisms, to develop and establish efficient methods in the induction of functional hematopoietic stem cells (HSC) from human induced pluripotent stem cells (iPSC), and in the differentiation of the HSC to different blood lineage cells.

A PhD degree in cell and molecular biology (or equivalent) is essential. The candidate will focus on HSC induction from both human embryonic stem (ES) cells and iPSC, and the following colony forming and their detection. Laboratory experiences with iPSC culture, HSC induction, colony forming units assay, fluorescence flow cytometry, MACS, immunocy to chemistry, molecular cloning and viral package would be desirable. A good level of knowledge and research experience in iPSC reprogramming and hematopoiesis are preferred. In addition, the candidate will be expected to demonstrate independent, critical and innovative thinking.

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Midlands of England