Research Fellow

The University of Edinburgh - The Roslin Institute

This is an exciting opportunity for an enthusiastic and motivated postdoctoral scientist to participate in a major new project, funded by the UK Department of Health, to evaluate the performance of blood-based diagnostic tests for prion diseases during preclinical infection. You will work closely with a large interdisciplinary team of scientists involved in related projects at the Roslin Institute and National Creutzfeld-Jakob Research and Surveillance Unit (NCJDRSU), as well as collaborators in the UK and internationally. The position will require adaptation of diagnostic assays based on misfolded protein capture, amplification and detection for application in an animal model, followed by comparative testing of the assays on a unique archive of preclinical blood samples.

You will have a have a PhD (or be near completion) in a relevant discipline and demonstrable experience and proficiency in range of biochemical and molecular techniques, particularly gene cloning/mutagenesis, protein expression and purification, and immunoassays (ELISA, Western blotting). You must be able to communicate complex information clearly, in writing and orally, for scientific and lay audiences, and have a peer-reviewed publication record appropriate to their level of experience. Excellent organizational and interpersonal communication skills are also required to ensure coordination of efforts among different research partners. Experience of working with infectious pathogens at Containment Level 2 or 3, of in vitro protein misfolding assays and/or development of blood-based diagnostic tests, would be an advantage.

Informal enquiries about the position can be directed to Dr Fiona Houston at:

For more information and to submit an application, please use the ‘apply’ button below.

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