Research Assistant/Associate - Design of NanoMOF Capsules for Drug Delivery

University of Cambridge - Department of Chemical Engineering and Biotechnology

Research Assistant Grade 5 £25,728- £30,688

Research associate Grade 7 £31,604- £38,833

The Adsorption and Advanced Materials Laboratory, headed by Dr. David Fairen-Jimenez (http://people.ds.cam.ac.uk/df334), is looking for an outstanding postdoctoral research assistant/associate for a project involving the use of metal-organic frameworks (MOFs) in drug delivery applications, to start on Q1 2018. The project is funded by the ERC Consolidator Grant NanoMOFdeli:

http://cordis.europa.eu/project/rcn/210035_en.html

This project focuses in the development of nanocarriers based on metal-organic frameworks (MOFs) - one of the most exciting developments in recent porous materials science - to encapsulate small drugs and macromolecules such as siRNA for cancer therapy. These macromolecules are potentially the most powerful anti-cancer drugs that exist, but still there is no efficient way of getting them delivered specifically to the tumour. Given the challenging nature of the drug delivery problem for cancer therapy, this project is based on several interrelated main concepts, and therefore a high level of collaboration skills are required. In particular, the candidate is expected to work in the design of bio-compatible MOFs for drug delivery applications; the post-synthesis treatment of MOFs to enhance drug delivery properties; and the identification of optimal properties (i.e. pore size distribution, surface area, pore volume) and surface chemistry of MOFs for siRNA delivery. The work will benefit from close collaborative work about the performance of the materials developed in vitro and in vivo.

The candidate must have a strong background in the area of MOF and organic synthesis as well as characterisation techniques, including a including a PhD in chemistry, materials science or in a relevant physical science discipline. Experience in drug delivery is not required. The candidate must be highly motivated and should have a strong academic record in terms of publications. The ability to work both as part of a team, and independently, coupled with excellent communication, organisational and problem solving skills are also required. The duties / responsibilities of this post include developing and driving research objectives; writing up work for presentations, publications and grant applications; collaborating with academic and industrial partners; assisting in the supervision of PhD research projects, and delivering seminars. It is expected that the candidate will contribute substantially to the future direction of the project.

For further information contact by Dr. David Fairen-Jimenez (df334@cam.ac.uk).

Further information about the Department is available here: www.ceb.cam.ac.uk.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy and to view further information about the role, please visit:

http://www.jobs.cam.ac.uk/job/15958. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

Applicants should ensure their application is complete and submitted by Midnight on the closing date.

Please quote reference NQ14187 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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South East England