PhD Studentship - Sensory Regulation of Dopaminergic Neurons

University of Sheffield

Fully Funded PhD Scholarship in Psychology at the University of Sheffield

This is one of many projects in competition for the current funding opportunities available within the Department of Psychology

Project title: Sensory regulation of dopaminergic neurons

Primary supervisor: Prof P Overton

Project description: The neurotransmitter dopamine is implicated in a wide range of brain processes and dysfunction of the dopamine systems leads to severe neurological and psychiatric problems. However, the precise function of the dopamine signal is still being hotly debated. Our approach to this problem has been to study the properties of the systems which supply information to the dopamine systems, in particular those which provide sensory information. Recent evidence suggests that dopamine systems receive visual information from the superior colliculus, a relatively primitive multimodal structure in the midbrain. This has important implications for the kind of information which the dopamine signal can carry, but we’re unsure how generalizable these implications are – i.e. whether the colliculus is also the source of other sensory inputs to the dopamine systems. That said, both the colliculus and dopamine systems both respond to auditory stimuli, and hence the visual circuitry may generalise to audition. This issue will be investigated using a combination of in vivo extracellular recording and tract tracing neuroanatomy. The eventual decoding of the dopamine signal will not only shed light on important aspects of brain function but will ultimately lead to the development of new treatments for dopamine-related disorders.

Start date: 1 October 2018

Requirements: Applicants must have a minimum of a first class or high upper second-class undergraduate honours degree and a distinction or high merit at Masters level in psychology or a related discipline.

Funding: Tuition fees £4,194 per year Living Expenses £14,500.00

Science Graduate School

As a PhD student in one of the science departments at the University of Sheffield, you'll be part of the Science Graduate School. You'll get access to training opportunities designed to support your career development by helping you gain professional skills that are essential in all areas of science. You'll be able to learn how to recognise good research and research behaviour, improve your communication abilities and experience the breadth of technologies that are used in academia, industry and many related careers. Visit www.sheffield.ac.uk/sgs to learn more.

For further details and the application process please visit:

www.sheffield.ac.uk/postgradapplication

Closing date for applications is 5pm Wednesday 24 January 2018

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Type / Role:

PhD

Location(s):

Northern England