Research Assistant - Spinal Muscular Atrophy

University of Oxford - Department of Physiology, Anatomy and Genetics

Applications are invited for a Research Assistant to join Professor Matthew Wood’s laboratory to further develop AONs with stereopure chemistry to target the human SMN gene. This is an exciting opportunity to work at the interface between academic research and drug discovery to contribute to the discovery of a clinical product for spinal muscular atrophy (SMA).

You will support a postdoctoral scientist in development and optimisation of new experimental protocols required to achieve the research objectives of this project. You will take responsibility for the day-to-day management of mouse colonies and carry out standard molecular biology techniques mostly involving processing and analysing animal tissue. You will also collaborate in the preparation of scientific reports and journal articles and the presentation of papers.

You must hold an undergraduate degree or equivalent in a relevant area of research. The applicant must have previous experience in standard molecular and cellular biology techniques, in particular, experience with RT-PCR or qPCR methods, Western blotting and with cell culture techniques. Previous experience working with animal models is also highly desirable. The ability to communicate effectively with others, particularly with regard to the presentation of scientific data is essential.

You will be based in the Le Gros Clark Building in the Department of Physiology, Anatomy and Genetics at the University of Oxford. The position is funded by WAVE to 31 March 2019. An early start to this post is essential.

Owing to the nature of this position, any offer of employment with the University will be subject to a satisfactory security screening.

The closing date for applications is 12.00 midday on 4 January 2019. Interviews will be held the week beginning Monday 8 January 2019.

Please note that the University of Oxford's retirement policy has changed. With effect from 1 October 2017, all employees at Grade 8 and above have a retirement age of the 30 September before the 69th birthday. All employees at Grades 1-7 do not have a set retirement age. Further details are available here:

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South East England