Research Fellow

University of Leeds - Leeds Institute of Cancer & Pathology (LICAP) - Infection and Immunity

Are you an ambitious researcher with a degree, PhD and experience in bioinformatics? Do you want to understand clonal evolution in a range of haematological diseases mechanisms, and have your research make a direct impact on the understanding of underlying processes in these diseases?

You will pursue a project whose primary aim is the assessment of the evolution of rare, treatment resistant clones from two chronic lymphocytic leukaemia (CLL) clinical trials ADMIRE and ARCTIC, led by Professor Peter Hillmen. The project builds on previous work using Next Generation Sequencing to identify rare mutations which lead to treatment resistance. It will utilise skills in Illumina next generation sequence analysis, use of the MARC1 cluster, development of bioinformatics tools and statistical modelling of rare mutant detection and clonal evolution.

You will work independently and as part of a larger team of researchers, to develop research objectives/proposals and to set the direction of the research project and team. You will proactively assess progression and suggest improvements, prepare collaborative funding proposals and engage in knowledge-transfer activities.

With a science degree and PhD, and a strong background in bioinformatics, mutation and statistical models, you will work closely, interactively and collaboratively with the project team, using your excellent communication and interpersonal skills.

To explore the post further or for any queries you may have, please contact:

Dr Darren Newton, Clonal Evolution Group Leader , Tel: +44 (0)113 343 8031, e-mail:

Further Information

The University of Leeds is committed to providing equal opportunities for all and offers a range of family friendly policies. The University is a charter member of Athena SWAN and holds the Bronze award. The School of Medicine gained the Silver award in 2016.We are committed to being an inclusive medical school that values all staff, and we are happy to consider job share applications and requests for flexible working arrangements from our employees.

Location: Leeds - St James University Hospital

Faculty/Service: Faculty of Medicine & Health

Category: Research

Salary: £32,548 to £38,833 p.a. (a maximum of £35,550 is available due to funding limitations)

Contract Type: Fixed Term (3 years - research funded)

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Northern England