Research Assistant in Muscular Dystrophy

University of Oxford - Physiology Anatomy and Genetics

Duchenne muscular dystrophy (DMD) is a devastating muscle wasting disorder caused by the lack of the integral protein dystrophin. We have recently shown that circadian rhythm is disrupted in dystrophic mice as a direct result of the lack of dystrophin protein and the objective of this project is to characterise the circadian-metabolic profile in multiple metabolic tissues of dystrophic mice, so that we may work to devise strategies to augment metabolism and improve muscle phenotype.

We are looking for a highly motivated, experienced research assistant to join the dynamic and highly collaborative lab of Professor Matthew Wood. The post holder will conduct their own research, bring new molecular and animal experimentation techniques to the lab, and be responsible for the day-to-day planning and execution of the project, in particular planning animal experiments, optimising new experimental protocols, analysing results and running experiments to achieve the research objectives of this project.

You must be familiar with basic molecular cell-biology techniques (experience with RT-PCR or qPCR methods and Western blotting) and cell culture procedures. You must have a personal animal licence (PIL) and be proficient in animal handling and husbandry, with expertise in a number of experimental procedures. It is imperative that you are able to work independently and be responsible for day-to-day planning, execution and analysis of experiments, but also be able to work collaboratively if required.

This post will be funded by Muscular Dystrophy UK for up to 5 months in the first instance, with a possible additional 13 months.

In addition to salary you will receive a generous annual leave entitlement and excellent development opportunities. Benefits package includes pension, childcare assistance and leisure facilities.

The closing date for applications is 12.00 midday on Friday 2 February 2018. Interviews are likely to be held Tuesday 13 February 2018.

Please note that the University of Oxford's retirement policy has changed. With effect from 1 October 2017, all employees at Grade 8 and above have a retirement age of the 30 September before the 69th birthday. All employees at Grades 1-7 do not have a set retirement age. Further details are available here: www.ox.ac.uk/about/jobs/preemploymentscreening.

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=132798

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South East England