Postdoctoral Training Fellow

The Francis Crick Institute

Contract: Fixed-term (4 years), full time

Short summary

An exciting opportunity to be part of a pioneering biomedical research institute, dedicated to innovation and science. We are looking for a highly motivated Postdoctoral Training Fellow to work across three laboratories (Charles Swanton, Erik Sahai and Julian Downward’s) and in close collaboration with the Experimental Histopathology and FACS/CyTOF Laboratories at the Francis Crick Institute is now available.  The post-holder will develop multi-parametric immunological tools to image the evolving cancer microenvironment using mass cytometry analyses and will be expected to have a broad interest in the tumour microenvironment and/or tumour imaging technologies using techniques such as mass cytometry. The post-holder will work with the EHP/FACS CyTOF laboratories at the Francis Crick Institute and within the TRACERx team and Downward/Sahai laboratories to develop imaging tools to quantify dynamic changes in cellular populations as tumours evolve over space and time from primary through to metastatic disease. The postdoc will be expected to work within a multidisciplinary team leading to the development of software algorithms to quantify the tumour microenvironment and cell-to-cell interactions in an objective manner. The work will leverage over 3000 primary and metastatic tumour regions from 600 patients from the TRACERx lung cancer study and lead to the development of state-of-the-art imaging technologies to establish new treatment paradigms to maximise the potential of the tumour microenvironment to limit tumour evolution and adaptation. The successful applicant will have good communication and organisations skills and a PhD in a relevant area (or be in the final stages of completion).

Research websites at:

This role will report to Professor Charles Swanton, Dr Erik Sahai and Professor Julian Downward.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

The closing date for applications is 09 February 2018 at 23:30.

All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

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