Postdoctoral Scientist – Cell Biology

MRC Laboratory of Molecular Biology

Applications are invited for a Postdoctoral Scientist position in the Group of Dr Simon Bullock in the Cell Biology Division of the Laboratory of Molecular Biology (LMB) in association with Dr Douglas Ross-Thriepland and Dr Roger Clark in the High Content Biology team, AstraZeneca (AZ).  This is an exciting opportunity for you to break new scientific ground in the regulation of intracellular cargo transport. Using AstraZeneca’s world leading arrayed-CRISPR screening platform you will identify novel factors that orchestrate the transport of cargos by microtubule motors. You will then conduct mechanistic studies at the LMB in order to shed light on how these factors regulate cargo transport.

You should have a PhD in a relevant subject (e.g. cell biology, functional genomics, high content imaging) or due to complete a PhD in a relevant subject within 6 months of the application deadline.  You should have expertise in the application of state-of-the-art fluorescence microscopy platforms to study cellular biology. You should also have experience with confocal and widefield imaging and with cell culture and basic molecular biology techniques.  Experience in functional genomic (e.g. CRISPR or RNAi) and high content/multivariate image and data analysis would be highly desirable.

The successful candidates will be awarded an MRC Career Development Fellowship/MRC Postdoctoral Training Scheme, for a fixed-term period. This is a training and development position for a Postdoctoral Scientist who has recently completed doctoral studies or is moving into a new research discipline.

The MRC Laboratory of Molecular Biology is one of the birthplaces of molecular biology and excels at deciphering the molecular mechanisms of life.  It provides an unsurpassed environment for both new and established researchers.  Scientists are drawn to the LMB from all over the world, creating a lively and international community for the exchange of ideas and technical innovation.

Working for the MRC provides a whole host of benefits including a final salary pension scheme, Benenden Healthcare membership and excellent holiday entitlement.  You will also have access to employee shopping/travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers. 

For further information of the research undertaken at the LMB, please visit:

For informal enquiries please contact Dr Simon Bullock ( or visit the group's website:

To apply and access full details of the vacancy please visit our job board at If you are unable to apply online please contact us at

Closing date: 1 March 2018.

Final appointments will be subject to a pre-employment screening.

The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme

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