Research Associate/Fellow (Fixed Term) MED043118

University of Nottingham - School of Life Sciences

Applications are invited for the above post in the The Centre of Membrane Proteins and Receptors (COMPARE), School of Life Sciences within the Faculty of Medicine and Health Sciences.The purpose of the role is to establish innovative biophysical approaches to determine ligand binding, oligomerisation and stability of GPCRs in living cells and model systems using purified proteins. To establish innovative single molecule signalling assays providing real-life kinetic information. 

The role will involve characterising the effects of mutations on ligand binding, signalling properties and stability of proteins, estimating compound or proteins parameters by direct fitting of data to current mathematical models of ligand-receptor interaction and signalling. 

In addition, the role will also involve structural studies of receptor-ligand complexes. The researcher will also be expected to present results at internal and external scientific meetings, write reports and papers, participate in writing grants, and be involved in supervision of undergraduate and PhD students.

Candidates should have a PhD(or be close to completion) or equivalent in pharmacology, biochemistry, biophysics, structural biology or related discipline.

This full-time fixed-term post is available from date of appointment for 2 years. Job share arrangements may be considered. 

COMPARE is a unique collaboration between the universities of Birmingham and Nottingham. Bringing together leading researchers, keen on developing novel methods for visualising single membrane proteins, as well as identifying new approaches for the prevention and treatment of cancer and cardiovascular disease.(

Informal enquiries may be addressed to Dmitry Veprintsev, tel: 0115 82 30671 or email Please note that applications sent directly to this email address will not be accepted.

The University of Nottingham is an equal opportunities employer and welcomes applications from all sections of the community.

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Midlands of England