Postdoctoral Research Associate in Cellular Immunology

University of Oxford - Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences

We are seeking a Postdoctoral Research Scientist to join the new research group of Dr Luke Jostins-Dean at the Kennedy Institute of Rheumatology, University of Oxford. You will join a dynamic and successful group studying the biology of inflammatory bowel disease (IBD) risk genes in human tissue. This project will be jointly supervised by Dr Jostins-Dean’s computational group and by Professor Fiona Powrie’s mucosal immunology group.

The aim of the project is to investigate the cell types and conditions in which IBD risk genes are expressed, to develop techniques to measure their function in human cells, and to assess genetic and prognostic correlates of these functions in patient samples. This project involves cell culture and immune cell stimulation, development of flow and mass cytometry panels, single-cell RNA-seq and high-throughput cell screening. You will be an enthusiastic, motivated, highly organised scientist possessing knowledge and good practical experience in immunology with an ability to produce work to a high standard, as well as testing hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. This project involves close collaboration between computational researchers and experimental immunologists, and you will have the opportunity to learn more about statistical and computational approaches to studying the human immune sys  tem. In turn, you will help teach computational researchers how to integrate experimental immunology into their research.

You will hold a PhD degree (or near completion) or equivalent in immunology. Experience of and proven research skills in cellular and molecular immunology and working with flow or mass cytometry as well as excellent communication skills with the ability to present results clearly and logically, working co-operatively as part of a team as well as independently, are also essential capabilities for this post. Experience working with cell cultures and human blood and tissue samples would be desirable.

This is a full-time appointment fixed-term until 31 December 2019 in the first instance.

You will be required to upload a CV and a supporting statement as part of your online application.

The closing date for applications is 12.00 noon on Wednesday 11 April 2018.

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South East England