Research Assistant - Mass Spectrometry/Ubiquitin Biology Group

University of Oxford - Target Discovery Institute (TDI)

NDM Research Building
Old Road Campus 

We are seeking to appoint a highly motivated individual for the role of a Research Assistant to reinforce the Ubiquitin Proteolysis research team within the TDI Mass Spectrometry Laboratory.

The successful candidate will support the laboratory in the characterisation of novel small molecule inhibitor candidates (generated within the Cancer Research UK – Forma Therapeutics DUB Alliance) targeting deubiquitylating enzymes (DUBs). The project will entail the study of DUB inhibitor activity and selectivity profiles, in vitro and in living cancer cells, using activity-based probes and a number of mass spectrometry and proteomic approaches.

You will have a degree either in biology, chemistry or biotechnology and experience in handling cells and tissue culture. In addition, you will have familiarity with biochemistry techniques (e.g. Immunoblotting, immunoprecipitation, pull-down, in vitro enzymatic activity assays) and a responsible nature with a methodical and careful approach to working in the laboratory independently. You will have the opportunity to be trained in advanced mass spectrometry and proteomics workflows.

This full-time position is fixed-term for 2 years in the first instance.

Further particulars, including details of how to apply, can be obtained from the document below. Applications for this vacancy should be made online and you will be required to upload a CV and supporting statement as part of your application.

The closing date for this position will be 12.00 noon on Thursday 12 April 2018.

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South East England