Senior Postdoctoral Bioinformatician in Diabetes Genetics

University of Oxford - Wellcome Centre for Human Genetics

Wellcome Centre for Human Genetics, Roosevelt Drive, Headington, Oxford/Oxford Centre for Diabetes Endocrinology and Metabolism, Churchill Hospital, Headington, Oxford

Grade 8: £39,992 - £47,722 with a discretionary range to £52,132 p.a.

Applications are invited for a Senior Postdoctoral Bioinformatician in Diabetes Genetics at the University of Oxford. You will be based at the Wellcome Centre for Human Genetics and the Oxford Centre for Diabetes Endocrinology and Metabolism.

The principal focus of this work will be related to the detection and functional characterisation of genetic variants associated with type 2 diabetes and related traits, including the complications of diabetes. In this post, you will provide leadership in developing and implementing a wide range of statistical and bioinformatics approaches within a multi-disciplinary team. The post involves responsibility for the integrated analysis of multiple, complex data sets to which we have access (including genetic, epigenomic, proteomic, metabolomic, physiological and clinical data), to address questions of mechanistic inference and translational value.

You will hold a PhD or equivalent degree in a relevant scientific subject with extensive, relevant, experience as a postdoctoral research in academia, biotech, or pharma. You will have demonstrable experience in the analysis of large-scale, highly-dimensional scientific data including those generated by GWAS, exome/whole genome sequencing and sequence-based functional assays (e.g. RNA-Seq, ATAC-Seq). You will have experience in the integration of diverse large-scale datasets, understanding of the key biological systems perturbed in type 2 diabetes, and be highly proficient in the use of programming and scripting languages (Unix, R, PERL, Python). Experience in network analysis and deep-learning approaches would be desirable. You will have a strong publication record for your career stage, proven ability to supervise staff and students and experience of developing scientific techniques and/or computational pipelines.

This position is fixed-term for 2 years in the first instance and funded by NIH, Foundation of the NIH and the European Union.

Please quote ref. 133769 on all correspondence. You will be required to upload a CV and supporting statement as part of your online application.

Only applications received before 12.00 midday on Monday 23 April 2018 can be considered.

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