Research Assistant/Associate in Cancer Immunology (Fixed Term)

University of Cambridge - Department of Pathology

We are seeking an enthusiastic and dedicated postdoctoral researcher to join Dr Louise Boyle's group (http://www.path.cam.ac.uk/directory/louise-boyle) at the Department of Pathology, University of Cambridge. The laboratory focuses on understanding the mechanism of peptide selection for immune recognition by major histocompatibility complex (MHC) molecules.

This position, funded by Cancer Research UK, will explore whether manipulation of a novel antigen presentation checkpoint can enhance the repertoire of tumour antigens presented for immune recognition.  The successful candidate will work closely with our co-investigator Dr Maike de la Roche at the Cancer Research UK Cambridge Institute (http://www.cruk.cam.ac.uk/users/maike-de-la-roche). The laboratory at the CRUK CI is ideally suited to investigate T cell responses in the tumour microenvironment. 

The postdoctoral candidate will be expected to hold a PhD, or equivalent qualification, in Immunology, Cancer biology or related discipline and have a proven track record of success in biomedical research. Where the successful applicant does not yet have a PhD, they will normally be under-appointed as a Research Assistant (salary of £28,936) in a Research Associate post (on the understanding that they will be appointed as a Research Associate (salary of £31,604) upon successful completion of their PhD). The higher Research Associate salary should be backdated to the submission date of their thesis or start date whichever is the later.

Candidates should have experience of tumour immunology, culture and manipulation of tumour cell lines, flow cytometry, immunohistochemistry as well as biochemistry and molecular biology techniques. A personal animal licence would be beneficial. Previous experience using CRISPR-Cas9 and multi-parameter flow cytometry and CyTOF would also be advantageous.

The successful applicant will become a valued member of a multi-disciplinary group and will be expected to have strong written and oral communication skills as well as an ability to supervise students.  The applicants should have the ability to design and carry out research both independently and as part of a team. Other duties/responsibilities are outlined in the Further Information document.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy and to view further information about the role, please visit:

http://www.jobs.cam.ac.uk/job/17142. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the 'Apply online' button and register an account with the University's Web Recruitment System (if you have not already) and log in before completing the online application form.

Interviews are likely to take place week commencing 14th May 2018.

General queries should be directed to Irene Piper, jobs@path.cam.ac.uk or 01223 333940.

Please quote reference PK15235 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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South East England