PhD: Novel Methods of Synthesising Circulation Metabolites of Natural Products

University of Hull - School of Mathematics and Physical Sciences (Chemistry)

To celebrate the University's research successes, the University of Hull is offering a full-time UK/EU PhD Scholarship or International Fees Bursary for candidates applying for the following project in Chemistry:

Novel methods of synthesising circulation metabolites of natural products

Closing date: - Monday 18th June 2018

Studentships will start on 17th September 2018

For further information contact the supervisors Dr Huw Jones (huw.jones@hull.ac.uk).

This project is co-supervised by Dr Huw Jones, Prof. Nicole Pamme, and Dr Kevin Welham in the School of Mathematics and Physical Sciences (Chemistry).

Plant-derived polyphenols are an interesting class of natural product that have been identified to have some pharmacological activities in a range of disease states including cardiovascular diseases (Molecular Nutrition and Food Research, 60, 4, 787-797).  These compounds undergo significant metabolic processing in humans, however these metabolites are not available for use in in vitro drug screening approaches, due to substantial challenges using traditional synthesis methods.  This project will utilise existing expertise in microfluidic synthesis technology at the University of Hull, to develop and characterise such devices for the synthesis of polyphenolic metabolites. 

Applicants should have an undergraduate degree (1st class) or Masters degree in chemistry or biochemistry.  Applicants should have knowledge or practical experience of microfluidic technology and its application to synthesis, and practical experience of analytical chemistry techniques (e.g. HPLC/LC-MS, NMR, etc.).  Enquiries should be directed to Dr Huw Jones (huw.jones@hull.ac.uk).

To apply for this Scholarship please click on the Apply button

http://www.hull.ac.uk/choose-hull/study-at-hull/admissions/postgraduate/how-to-apply.aspx

Full-time UK/EU PhD Scholarships will include fees at the ‘home/EU' student rate and maintenance (£14,777 in 2018/19) for three years, depending on satisfactory progress.

Full-time International Fee PhD Studentships will include full fees at the International student rate for three years, dependent on satisfactory progress.

PhD students at the University of Hull follow modules for research and transferable skills development and gain a Masters level Certificate, or Diploma, in Research Training, in addition to their research degree.

Successful applicants will be informed of the award as soon as possible and by 16th July 2018 at the latest.

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Type / Role:

PhD

Location(s):

Northern England