Rosalind Franklin Institute
The Rosalind Franklin Institute is a technology institute for life science, creating innovative technologies that transform our understanding of life. Our technologies, borne out of innovation in physical sciences, create collaborations and new avenues in life science which will lead to new therapeutics and advance our understanding of human biology.
We are funded by the UK Research Innovation through the Engineering and Physical Sciences Research Council.
The spectrum of tools under development at the Franklin are individually extraordinary, but when combined at the Franklin’s Hub, they allow us to develop tomorrow’s healthcare innovations.
As an organisation we appreciate that our people are one of our biggest strengths. With world-class laboratory facilities, we are committed to supporting your learning and development, helping you gain the skills you need to succeed in your role. Regardless of your level of experience and your role, we can assist you with building your expertise, experience and professional qualifications at key career stages.
We pride ourselves in creating an inclusive culture with remarkable resources and facilities where we can encourage creativity and celebrate diversity.
Research and Impact
Through a unique integration of disciplines, our mission is to develop disruptive new technologies designed to tackle major challenges in health and life science. This will accelerate the discovery of new treatments for chronic diseases affecting millions of people around the world.
Our teams are aligned across six technology and life science challenges, alongside two emerging areas of interest. Our scientists, technologists and software engineers working together in a multi-disciplinary and collaborative environment at our state-of-the-art research facility at Harwell in Oxfordshire.
Technology Innovation Challenges
- Multidimensional Imaging
- Integrated Chemical Imaging in Cells and Tissues
- Artificial Intelligence and Informatics for Predictive Biology
- Molecular Perturbations: Chemistry Engineering Biology
- Quantitative Biology Across Scales
Life Science Challenges
- How Pathogens Interact with Human Cells
- Emerging Interest Area: Cell-cell Interactions
- Emerging Interest Area: Structural Cell Pathology
For more information on the Franklin’s Challenges click here.
Meet Our PhD Student
Dimitrios Ioannidis – PhD Student
Thesis title: Visualising adhesion complexes in intestinal organoids via super-resolution STED
Dimitrios graduated with a MRes in Medical and Molecular Biosciences from Newcastle University where he also obtained his BSc in Biochemistry. . As his interest in protein research has developed over the years, he decided to embark on his PhD journey at the Rosalind Franklin Institute.
At the Franklin, Dimitrios’s research is focused on visualising protein adhesion complexes in intestinal organoids. With his research Dimitrios will try to uncover the nanoscale organisation and dynamics of the tight junctions in the gut in the context of inflammation using patient derived organoids. To achieve these goals, he is using super resolution STED microscopy and other advanced fluorescent microscopy techniques.
Here is what Dimitrios has to say about the PhD programme: “Here is what Dimitrios has to say about the PhD programme: “"As a PhD student at the Franklin I am very fortunate to sit in the interface between academia and industry which allows me to contribute to the development of new technology that I can then utilise to answer exciting biological questions.”