|Salary:||£28,098 to £38,833 per annum|
|Placed On:||8th August 2018|
|Closes:||10th September 2018|
To make a leading contribution to a project, as part of an EPSRC/NIHR Global Challenge Research Fund programme aimed at developing novel field-based molecular diagnostic technologies in Africa (https://tinyurl.com/y6u5z6f7). You will primarily work with Professor Jon Cooper and Dr. Julien Reboud on the development of paper-based assay tools for field testing of both parasitic infectious and non-communicable diseases (see e.g. https://www.epsrc.ac.uk/blog/paperinfectiousdiseases/ and www.glasgow.ac.uk/origami).
In the Advanced Diagnostics group in the Division of Biomedical Engineering we have developed a portfolio of technologies to enable low-cost, low-power (no power or battery-powered), point-of-use advanced diagnostic devices. Using paper-folding techniques, we have shown that resource-intensive assays, such as nucleic acid tests to detect the genetic material of the pathogen, can be delivered in an ultra-low cost, portable format. These sensors have been produced using hot-wax printing and the assay, which can be performed by a non-expert, uses paper-folding (origami) to bring sample and reagents into contact (see http://tinyurl.com/z3vv7fe).
The specific aspect of the project you will undertake will focus on the development of molecular assays and their integration into the technology platform so that it can be used for rapid point-of-care diagnostics in the field, primarily targeting malaria and schistosomiasis. These two diseases infect more than 415 million people across the world and negatively affect many more. Importantly, you will work at the interface between biologists and engineers as well as with researchers from the Health Technology Assessment unit to evaluate the impact of the platforms you develop in the field. In addition, you will have the opportunity to test the devices in Rwanda and Uganda.
This job requires a knowledge of molecular biology and its application in microfluidics for point-of-care diagnostics as well as a creative aptitude and practical approach to problem solving coupled to the development of user friendly systems. It is anticipated that the successful candidate will be able to contribute to the formulation and submission of research publications and research proposals as well as help manage and direct this complex and challenging project, as opportunities allow.
Standard Terms & Conditions
Salary will be on the University’s Research and Teaching Grade, level 6/7, £28,098 - £31,604/£34,520 - £38,833 per annum.
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