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Research Fellow

University College London - Research Department of Genetics, Evolution and Environment

Location: London
Salary: £35,328 to £42,701 per annum, inclusive of London Allowance. Grade 7
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 28th September 2018
Closes: 29th October 2018
Job Ref: 1753077
 

The appointment will be on UCL Grade 7. The salary range will be £35,328 - £42,701 per annum, inclusive of London Allowance.

Deep homology of spiral cleavage in lophotrochozoan embryology: Comparative single cell sequencing of early embryonic stages of spirally cleaving animals. Lophotrochozoan animal phyla (including molluscs, annelids and flatworms) diverged in the Cambrian. Despite this great evolutionary distance, these animals share a unique pattern of early cell divisions called spiral cleavage.

Professor Max Telford's research group want to test whether this extraordinary phenotypic conservation is underpinned by comparable genetic conservation and are wishing to appoint a postdoctoral research associate to work on this project.

The three year project, funded by the Leverhulme trust, aims to read the genes expressed in individual early blastomeres of different spirally cleaving spiralian embryos and to compare the genetic programmes of this process across phyla.

Using newly-developed single cell sequencing technology, we will sequence mRNAs of equivalent blastomeres from different phyla to establish the degree to which developmental deployment of gene expression is conserved across Lophotrochozoa. Ultimately we aim to understand the genetic basis of the extraordinary conservation of this developmental process. The successful applicant will co-design, develop and refine molecular biological experiments in order to obtain reliable data, and carry out analyses, critical evaluations, and interpretations under the supervision of Professor Telford.

This post is funded until 31 December 2021 in the first instance.

The successful applicant will have a PhD (or about to submit) in a relevant subject area along with excellent molecular laboratory skills and practical first-hand knowledge of more than one of the following: transcriptome sequencing, single cell sequencing, developmental biology and an interest in animal evolution.

UCL vacancy reference: 1753077

Applicants should apply online. To access further details about the position and how to apply please click on the ‘Apply’ button above.

For informal enquiries about the role, please email Professor Max Telford, m.telford@ucl.ac.uk . If you have any queries regarding the application process, please contact the Biosciences Staffing team at biosciences.staffing@ucl.ac.uk .

Closing Date: 29th of October 2018

Latest time for the submission of applications: 23.59.

Interview Date: TBC

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