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PhD Studentship: Rewiring Plant Gene Regulatory Networks (PATRON_E19DTP)

University of East Anglia - School of Biological Sciences

Qualification Type: PhD
Location: Norwich
Funding for: UK Students, EU Students
Funding amount: £14,777 per annum
Hours: Full Time
Placed On: 9th October 2018
Closes: 26th November 2018

Location Earlham Institute, Norwich
Start date: 1/10/2019
Closing date: 26/11/2018
No. of positions available: 1
Hours: Full-time
Contract: Temporary
Supervisor Nicola Patron

Project description

Plants have the ability to alter their growth and development in response to changes in their environment. They do this by altering the expression levels of large suites of genes. Previous work has shown that a small network of genes may be responsible for coordinating large-scale changes in gene expression in response to the detection of pathogens. To develop crops with the ability to deliver high yields in changing environments, we need to advance our understanding of how these networks function and how variations in sequences of the key genes that coordinate these networks affect plant responses. This project will investigate the role of candidate key controllers in a pathogen-response network, using a novel approach of designing synthetic genetic controllers to rewire the network. Our aims are to understand how the network is coordinated and to provide insights into how to breed or rationally engineer plants resilient to stress. The student will be based in the Patron Lab (Earlham Institute, Norwich) and will work in close collaboration with the Denby Lab (University of York) and the Morris Lab (John Innes Centre, Norwich). This exciting, collaborative and multidisciplinary project will employ a range of techniques including molecular plant biology, synthetic biology, genome engineering, systems biology and modelling. It would be suitable for a biologist with, or eager to acquire, computational skills. Training will be provided in all areas.

Person Specification UK 2:1 & English Language (6.5 overall, 6 in each section)

Funding notes For funding eligibility guidance, please visit our website: http://biodtp.norwichresearchpark.ac.uk/how-to-apply/funding-and-eligibility. Full Studentships cover a stipend (UKRI rate: £14,777pa – 2018/9), research costs and tuition fees at UK/EU rate and are available to UK and EU students who meet the UK residency requirements.  

Students from EU countries who do not meet the UK residency requirements may be eligible for a fees-only award. Students in receipt of a fees-only award will be eligible for a maintenance stipend awarded by the NRPDTP Bioscience Doctoral Scholarships. To be eligible students must meet the EU residency requirements.  

This project has been shortlisted for funding by the Norwich Biosciences Doctoral Training Partnership (NRPDTP). Shortlisted applicants will be interviewed as part of the studentship competition. Candidates will be interviewed on either the 8th, 9th or 10th January 2019. 

The NRP DTP offers postgraduates the opportunity to undertake a 4-year research project whilst enhancing professional development and research skills through a comprehensive training programme. You will join a vibrant community of world-leading researchers. All NRPDTP students undertake a three-month professional internship (PIPS) during their study. The internship offers exciting and invaluable work experience designed to enhance professional development. Full support and advice will be provided by our Professional Internship team. Students with, or expecting to attain, at least an upper second-class honours degree, or equivalent, are invited to apply. 

 For further information and to apply, please visit our website: www.biodtp.norwichresearchpark.ac.uk 

   
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