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Research Assistant Synthetic Chemistry

Cardiff University - Cardiff School of Biosciences

Location: Cardiff
Salary: £27,025 to £31,302 per annum (Grade 5)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 11th October 2018
Closes: 11th November 2018
Job Ref: 7887BR

A new major translational award has been awarded by the Medical Research Council, worth £2.5M. This complements an exciting and mature portfolio of Drug Discovery funding awarded to Prof Simon Ward and Prof John Atack from Cardiff University.   

The grant will look at Fragile X syndrome (FXS) - a leading inherited cause of autism and intellectual disabilities which affects approximately 1 in 5000 individuals. There are no currently approved drugs for the treatment of FXS which can cause a wide range of difficulties with learning, as well as social, language, attentional, emotional, and behavioural problems. There is therefore an urgent need for new therapeutic approaches for this disorder.

Proof of concept experiments have shown that inhibition of LIMK1 (a gene which provides instructions for making a protein that is highly active in the brain) could represents an attractive new therapeutic approach to FXS. A world leading team of specialists have been assembled and further scientist will be recruited to Cardiff to address the enormous challenge of bringing forward new medications for FXS. Collaborations will take place across the UK and will include Oxford University, University of Dundee as well as academic colleagues in Germany, San Francisco, Montreal and Chicago. We will also be working closely with The Fragile X Society, a charity who provide practical guidance to support to individuals and families affected by FXS. 

This will enable a link to patients and clinicians involved to help us work together effectively to work towards the mission to find an effective treatment for FXS. 

To contribute to research within Synthetic Chemistry, carrying out supporting work that helps lead to the publishing of research in high-quality journals. To pursue excellence in research and to inspire others to do the same.

The post will be based at Cardiff University and will be part of a multi-disciplinary drug discovery team. For informal inquiries, please contact

In Higher Education, female and BME (black and minority ethnic) staff are underrepresented in senior academic roles. Applications are therefore particularly welcome from applicants who identify as female and/ or BME. We also welcome applications from members of the LGBT+ Community.

This post is full-time, fixed-term and available until 31 January 2021. This Post will available from 1 February 2019.

Interviews will be held week commencing 19 of November.

Please be aware that Cardiff University reserves the right to close this vacancy early should sufficient applications be received.

Cardiff University is committed to supporting and promoting equality and diversity and to creating an inclusive working environment. We believe this can be achieved through attracting, developing, and retaining a diverse range of staff from many different backgrounds who have the ambition to create a University which seeks to fulfil our social, cultural and economic obligation to Cardiff, Wales, and the world.  In supporting our employees to achieve a balance between their work and their personal lives, we will also consider proposals for flexible working or job share arrangements.

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