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Postdoctoral Research Associate in Molecular Probes for TB

The University of Edinburgh - Chemistry

Location: Edinburgh
Salary: £33,199 to £39,609 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 7th December 2018
Closes: 20th December 2018
Job Ref: 046183

College of Science and Engineering

We are seeking to recruit a highly motivated and enthusiastic synthetic chemistry/technology-based post-doctoral researcher to join an exciting multidisciplinary team. You will join a newly funded EU Horizon 2020 project (Proposal title: Accurate, Rapid, Robust and Economical Diagnostic Technologies for Tuberculosis ARREST-TB) as part of a research team that spans across the Universities of Edinburgh and Heriot Watt with academic and industry partners in Spain, Italy, Russia and India.

Sputum smear microscopy is widely used to screen suspected pulmonary TB cases. However, currently these microscopy tests are performed in centralised facilities often remote from primary care and depend on colour-based methods (that rely on the ability of the mycobacterial outer membrane to retain hydrophobic dyes) that were developed over 100 years ago. These staining protocols require extensive processing and washing steps, resulting in as low as 20-30% sensitivity reported. The purpose of the job is therefore to:

  • Synthesis of a suite of chemical labels that will specifically stain Mycobacterium in sputum and hence allow accurate, rapid and ‘no-wash’ identification of suspected pulmonary TB cases.
  • The probes have to be stable, manufactured at low cost and be able to work in conjunction with frugal sputum processing/optical recording devices that will be developed by the Engineering team.

Informal enquiries about the post should be addressed to Dr Seshasailam Venkateswaran ( or Professor Mark Bradley (

Post is funded for 24 months, with a start date in January 2019 or as soon thereafter.

Closing Date: 20-DEC-2018 at 5pm GMT

For further particulars and to apply for this post please click on the 'apply' button above

The University of Edinburgh is a charitable body, registered in Scotland, with registration number SC005336.

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