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Ensembl Compara Project Leader

European Molecular Biology Laboratory (EMBL)

Location: Cambridge, Hinxton
Salary: £3,351 monthly starting salary after tax (Grade 7).
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 21st January 2019
Closes: 1st March 2019
Job Ref: EBI01359

Contract Duration: 3 years

The Ensembl project seeks a talented and motivated Project Leader to manage its activities in the area of comparative genomics. 

Ensembl is a world-leading project that integrates and annotates genomes from thousands of species across the tree of life, and serves them in a number of dynamic ways to the global scientific community. The Ensembl Compara team forms a critical component of this mission, developing and deploying pipelines and tools for comparing genes and genomes, by way of evolutionary trees, orthology/paralogy, multiple alignments and synteny. As global efforts to sequence the genomes of all species on earth begin to gather pace, this position will give you a prominent role in shaping Ensembl’s response to this exciting challenge.

Your role

You will be responsible for operational leadership of comparative genomics activities in Ensembl. Under the immediate supervision of the Eukaryotic Annotation Team Leader, you will lead the expansion of Ensembl’s comparative genomics resources to tens-of-thousands of species, with focus on the development of scalable pipelines for (a) inference of orthology and paralogy relationships, and (b) whole-genome pairwise and multiple alignments. You will also:

  • Manage and mentor a team 4-5 bioinformaticians/developers
  • Manage the team’s development and production work for Ensembl releases
  • Engage with users and other Ensembl teams to develop effective displays and APIs for comparative genomics data
  • Write reports and papers describing Ensembl comparative genomics resources
  • Represent the project relevant international consortia (such as the Quest for Orthologs)
  • Keep up-to-date with current research in comparative genomics tools and methods

You have

  • Broad knowledge of comparative genomics concepts and methods
  • Experience with using relational databases for biological data
  • Experience with designing and deploying complex analysis pipelines on an HPC cluster
  • Proficiency in at least one programming language (e.g. Perl or Python)

You will ideally hold a PhD or equivalent in Molecular Biology, Bioinformatics or related field with demonstrated experience in comparative genomics. Applicants with a MSc and appropriate experience will also be considered.

You will have excellent verbal and written communication skills to lead within a project where biologists and computer scientists work closely together. You will also be highly organized in order to meet the regular deadlines, reports and procedures across the wider Ensembl project.

You might also have

Although not essential, the ideal applicant might also have:

  • Experience with formal project management principles and techniques
  • Experience of working with the Ensembl platform
  • Expertise specifically in Perl and MySQL
  • Experience with working in large collaborative genomics projects

Why join us

The remuneration package comprises a competitive salary, a comprehensive pension scheme and health insurance, educational and other family related benefits where applicable, as well as financial support for relocation and installation. For more information about pay and benefits click here

What else do I need to know

To apply please submit a covering letter and CV through our online system.

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