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PhD Studentship: Alpha-synuclein aggregation in the pathogenesis of Parkinson's disease

Xi'an Jiaotong - Liverpool University - Department of Biological Sciences

Supervisor Names:

Principle supervisor:  Professor Mu Wang (XJTLU, Department of Biological Sciences)

https://www.xjtlu.edu.cn/en/departments/academic-departments/biological-sciences/staff/mu-wang

Co-supervisor: Dr. Jill Madine (University of Liverpool, Department of Biochemistry)

Project Description:

Parkinson's disease (PD) is the second most common neurodegenerative disease behind Alzheimer's disease. While the etiology of PD is not completely clear, a common link between both familial and sporadic forms of disease is the protein called -synuclein (aSyn). Even though the molecular mechanisms underlying aSyn aggregation remains unknown, protein-protein interactions and post-translational modifications on aSyn have been implicated to be associated with PD pathogenesis. Previous studies were impeded by the lack of a well-controlled cellular or animal model and high-accuracy measurement tools, some published data thus may be misleading. In this project, we will apply the cutting-edge proteomic technologies to systematically analyze aSyn containing protein complex and its post-translational modifications in samples derived from healthy and disease conditions. Our studies will provide important information about the role of aSyn in neurodegeneration and its potential in therapeutics.

For more information about doctoral scholarship and PhD programme at Xi’an Jiaotong-Liverpool University (XJTLU): Please visit

http://www.xjtlu.edu.cn/en/study-with-us/admissions/entry-requirements

http://www.xjtlu.edu.cn/en/admissions/phd/feesscholarships.html

Eligibility Criteria:

The candidate should have a first class or upper second class honours degree, or a master’s degree (or equivalent qualification), in Chemistry, Biology, Biochemistry, or related fields. Evidence of good spoken and written English is essential. The candidate should have an IELTS score of 6.5 or above, if the first language is not English. This position is open to all qualified candidates irrespective of nationality.

Degree: 

The student will be awarded a PhD degree from the University of Liverpool (UK) upon successful completion of the program. 

Funding:

The PhD studentship is available for three years subject to satisfactory progress by the student. The award covers tuition fees for three years (currently equivalent to RMB 80,000 per annum) and provides a monthly stipend of 5,000 RMB as a contribution to living expenses. It also provides up to RMB 16,500 to allow participation at international conferences during the period of the award.  It is a condition of the award that holders of XJTLU PhD scholarships carry out 300-500 hours of teaching assistance work per year. The scholarship holder is expected to carry out the major part of his or her research at XJTLU in Suzhou, China. However, he or she is eligible for a research study visit to the University of Liverpool of up to three months, if this is required by the project.

How to Apply:

Interested applicants are advised to email mu.wang@xjtlu.edu.cn the following documents for initial review and assessment (please put the project title in the subject line).

  • CV
  • Two reference letters with company/university letterhead
  • Personal statement outlining your interest in the position
  • Proof of English language proficiency (an IELTS score of 6.5 or above)
  • Verified school transcripts in both Chinese and English (for international students, only the English version is required)
  • Verified certificates of education qualifications in both Chinese and English (for international students, only the English version is required)
Qualification Type: PhD
Location: Suzhou - China
Funding for: UK Students, EU Students, International Students
Funding amount: ¥140,000
£15,632.68 converted salary* per annum (Covers tuition fee and stipend).
Hours: Full Time
Placed On: 23rd May 2019
Closes: 3rd July 2019
 
   
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* Salary has been converted at the prevailing rate on the date placed
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