|Salary:||Competitive with benefits, subject to skills and experience|
|Placed On:||12th July 2019|
|Closes:||12th August 2019|
Contract: Fixed-term, 4 years, Full time
Roles of metabolism in the developmental origins of health and longevity
A postdoctoral research post funded by the Wellcome Trust in the laboratory of Dr. Alex Gould is now available. This is an exciting opportunity to be part of a pioneering biomedical research institute, dedicated to innovative science. We are looking for a highly motivated researcher to identify the, as yet unknown, mechanisms by which dietary nutrients during development can have profound long-term effects upon adult metabolism and lifespan. The successful applicant will be able to choose from several Drosophila and mouse models that have been established in our lab (PMID: 21816278, PMID: 26451484, PMID: 29123106, PMID: 29515102 and unpublished). They will use a range of techniques including genetics, molecular biology, confocal microscopy, biochemistry, metabolomics as well as mass spectrometry imaging (PMID: 22246326). Access will be provided to state-of-the-art facilities in advanced light and electron microscopy, metabolomics and single-cell sequencing. Details of projects ongoing in the lab can be seen at www.agouldlab.com and at www.crick.ac.uk/research/labs/alex-gould. The successful applicant will have good communication and organisational skills and a PhD in a relevant area (or be in the final stages of completion).
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases. An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London. The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the largest biomedical research facility in one building in Europe. The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.
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