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EPSRC DTP PhD Studentship in Mathematics: In Vivo Verification of Proton Therapy: Derivation of Delivered Radiation Dose via Prompt Gamma Imaging.

University of Reading

Qualification Type: PhD
Location: Reading
Funding for: UK Students, EU Students
Funding amount: Tuition fees plus RCUK stipend
Hours: Full Time
Placed On: 29th July 2019
Closes: 30th September 2019
Reference: GS18-022

Project title:  In Vivo Verification of Proton Therapy: Derivation of Delivered Radiation Dose via Prompt Gamma Imaging.

Department/School: Mathematics and Statistics / SMPCS

Supervisors:  Marcus Tindall, Colin Baker and Tristan Pryer

Project Overview:   Conventional radiotherapy uses high energy beams of x-rays to destroy cancerous cells. Whilst modern radiotherapy techniques allow the radiation dose to be very accurately targeted to the tumour, some radiation is deposited in surrounding normal tissues, which can lead to treatment-related side effects which impact on a patient’s quality of life after treatment. The use of high energy protons, rather than x-rays, has the potential to reduce this radiation dose and so reduce the risk of side-effects. In order to fully realise this potential benefit, however, a number of technical challenges remain.

This project aims to develop accurate, efficient, and robust numerical algorithms for examining proton therapy delivery, specifically aiming to provide real-time verification that clinical proton treatments are delivered as intended. The successful candidate will work on cutting-edge mathematical modelling of proton therapy, evaluated against full Monte Carlo simulation of the underlying radiation transport using established Monte Carlo codes (e.g. FLUKA).  

The successful candidate will become a member of a dynamic Mathematical Biology Group in the Department of Mathematics and Statistics at Reading, which has a strong track record of working with industry and an ever increasing portfolio of clinically related projects. The project will be undertaken in collaboration with the Royal Berkshire NHS Foundation Trust, The National Physical Laboratory and Proton Partners International, providing the opportunity to develop interdisciplinary research skills in an emerging topic of substantial investment nationally.


  • Applicants should hold or expect to gain a minimum of a 2:1 Bachelor Degree or equivalent in Mathematics or another Mathematically based discipline.
  • Due to restrictions on the funding this studentship is open to UK/EU students.

Funding Details:   

  • Starts January 2020
  • 3 year award
  • Tuition fees plus RCUK stipend

How to apply:   

To apply for this studentship please submit an application for a PhD in Mathematics at

*Important notes*

  • Please quote the reference ‘GS18-022’ in the ‘Scholarships applied for’ box which appears within the Funding Section of your on-line application.

Application Deadline: 

30th September 2019

Further Enquiries:  

Please note that, where a candidate is successful in being awarded funding, this will be confirmed via a formal studentship award letter; this will be provided separately from any Offer of Admission and will be subject to standard checks for eligibility and other criteria. 

For further details please contact

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